Transient expressions of doppel and its structural analog prionDelta32-121 in SH-SY5Y cells caused cytotoxicity possibly by triggering similar apoptosis pathway (Q39804076)

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English	Transient expressions of doppel and its structural analog prionDelta32-121 in SH-SY5Y cells caused cytotoxicity possibly by triggering similar apoptosis pathway	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Transient expressions of doppel and its structural analog prionDelta32-121 in SH-SY5Y cells caused cytotoxicity possibly by triggering similar apoptosis pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

prion protein family

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author name string

K Xu

1

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Europe PubMed Central

PubMed publication ID

14 September 2017

X Wang

2

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Europe PubMed Central

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14 September 2017

C Tian

3

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Europe PubMed Central

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14 September 2017

S Shi

4

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Europe PubMed Central

PubMed publication ID

14 September 2017

G R Wang

5

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Europe PubMed Central

PubMed publication ID

14 September 2017

Q Shi

6

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Europe PubMed Central

PubMed publication ID

14 September 2017

P Li

7

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Europe PubMed Central

PubMed publication ID

14 September 2017

R M Zhou

8

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Europe PubMed Central

PubMed publication ID

14 September 2017

H Y Jiang

9

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14 September 2017

Y L Chu

10

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Europe PubMed Central

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14 September 2017

X P Dong

11

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14 September 2017

publication date

29 August 2009

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Europe PubMed Central

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14 September 2017

Molecular Biology Reports

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Europe PubMed Central

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14 September 2017

37

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Europe PubMed Central

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14 September 2017

5

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14 September 2017

2549-2558

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Europe PubMed Central

PubMed publication ID

14 September 2017

Removal of the glycosylation of prion protein provokes apoptosis in SF126.

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https://api.crossref.org/works/10.1007%2FS11033-009-9772-3

21 January 2018

Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration

1 reference

https://api.crossref.org/works/10.1007%2FS11033-009-9772-3

21 January 2018

Prions prevent neuronal cell-line death.

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https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper(II) binding to the human Doppel protein may mark its functional diversity from the prion protein

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https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic mammalian prions

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https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

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https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two different neurodegenerative diseases caused by proteins with similar structures

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https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prion protein protects human neurons against Bax-mediated apoptosis

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https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doppel-induced cerebellar degeneration in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-autonomous PrP-Doppel interaction regulates apoptosis in PrP gene-deficient neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doppel-induced Purkinje cell death is stoichiometrically abrogated by prion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doppel-induced cytotoxicity in human neuronal SH-SY5Y cells is antagonized by the prion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cellular prion protein (PrPC) prevents apoptotic neuronal cell death and mitochondrial dysfunction induced by serum deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The N-terminus of PrP is responsible for interacting with tubulin and fCJD related PrP mutants possess stronger inhibitive effect on microtubule assembly in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doppel induces degeneration of cerebellar Purkinje cells independently of Bax

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel proteinaceous infectious particles cause scrapie

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Creutzfeldt-Jakob disease in a Chinese patient with a novel seven extra-repeat insertion in PRNP

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scrapie prion protein contains a phosphatidylinositol glycolipid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19728151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11033-009-9772-3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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