Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth (Q39773538)

14 September 2017

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth (English)

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14 September 2017

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18

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14 September 2017

8

Sagar Lonial

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14 September 2017

16

Fadlo R Khuri

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14 September 2017

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Titus J Boggon

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14 September 2017

Taro Hitosugi

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14 September 2017

Sumin Kang

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14 September 2017

Matthew G Vander Heiden

3

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14 September 2017

Tae-Wook Chung

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14 September 2017

Shannon Elf

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14 September 2017

Katherine Lythgoe

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14 September 2017

Shaozhong Dong

7

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14 September 2017

Xu Wang

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14 September 2017

Georgia Z Chen

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14 September 2017

Jianxin Xie

11

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14 September 2017

Ting-Lei Gu

12

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14 September 2017

Roberto D Polakiewicz

13

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14 September 2017

Johannes L Roesel

14

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14 September 2017

D Gary Gilliland

17

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14 September 2017

Jonathan Kaufman

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14 September 2017

Jing Chen

20

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14 September 2017

17 November 2009

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14 September 2017

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14 September 2017

2

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14 September 2017

ra73

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14 September 2017

97

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Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Tumor cell metabolism: cancer's Achilles' heel

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Pyruvate kinase M2 is a phosphotyrosine-binding protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Current status of tumor M2 pyruvate kinase (tumor M2-PK) as a biomarker of gastrointestinal malignancy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Hypoxia signalling controls metabolic demand

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Tumour M2-pyruvate kinase: a gastrointestinal cancer marker

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Pyruvate kinase type M2 and its role in tumor growth and spreading

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Pyruvate kinase type M2: a crossroad in the tumor metabolome

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

ZNF198-FGFR1 transforming activity depends on a novel proline-rich ZNF198 oligomerization domain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

22 September 2017

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast, and comparison with other normal tissues

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

The allosteric regulation of pyruvate kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

New structures of allosteric proteins revealing remarkable conformational changes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Aberrant expression of type I fibroblast growth factor receptor in human pancreatic adenocarcinomas.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Fibroblast growth factor receptor gene expression and immunoreactivity are elevated in human glioblastoma multiforme.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812789

Expression of FGF and FGF receptor genes in human breast cancer

17 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19920251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tumor-specific pyruvate kinase isoenzyme M2 involved in biochemical strategy of energy generation in neoplastic cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19920251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCISIGNAL.2000431

1 reference

14 September 2017

1 reference

14 September 2017

1 reference