STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL. (Q39730561)

14 September 2017

STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL (English)

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13 May 2020

5

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13 May 2020

Navin Kumar Verma

1

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13 May 2020

Aideen Long

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13 May 2020

author name string

Anthony M Davies

2

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13 May 2020

Dermot Kelleher

4

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publication date

5 March 2010

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Cellular & Molecular Biology Letters

14 September 2017

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13 May 2020

volume

15

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issue

2

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13 May 2020

page(s)

342-355

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https://scigraph.springernature.com/pub.10.2478/s11658-010-0008-2

13 May 2020

exact match

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The selective protein kinase C beta inhibitor enzastaurin induces apoptosis in cutaneous T-cell lymphoma cell lines through the AKT pathway

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Low FAS/CD95 expression by CTCL correlates with reduced sensitivity to apoptosis that can be restored by FAS upregulation

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The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine

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Resistance to activation-induced cell death and bystander cytotoxicity via the Fas/Fas ligand pathway are implicated in the pathogenesis of cutaneous T cell lymphomas.

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In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

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Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells

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Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells.

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

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Apoptosis: a review of programmed cell death

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Classification and prediction of survival in patients with the leukemic phase of cutaneous T cell lymphoma

21 January 2018

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Arsenic trioxide induces apoptosis of cutaneous T cell lymphoma cells: evidence for a partially caspase-independent pathway and potentiation by ascorbic acid (vitamin C).

21 January 2018

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Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness.

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Short interfering RNA (siRNA): tool or therapeutic?

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Expression of apoptosis regulators in cutaneous T-cell lymphoma (CTCL) cells.

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STAT family of transcription factors in cytokine-mediated biological responses

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Targeting STAT3 affects melanoma on multiple fronts

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STAT proteins as novel targets for cancer drug discovery

21 January 2018

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A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin

21 January 2018

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Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

21 January 2018

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Inhibition of STAT3 expression by siRNA suppresses growth and induces apoptosis in laryngeal cancer cells.

21 January 2018

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STAT3-stathmin interactions control microtubule dynamics in migrating T-cells

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Constitutive and interleukin-7/interleukin-15 stimulated DNA binding of Myc, Jun, and novel Myc-like proteins in cutaneous T-cell lymphoma cells

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12 December 2020

Cutaneous T-cell lymphoma/leukemia

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12 December 2020

Cutaneous T-cell lymphoma

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12 December 2020

Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

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12 December 2020

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Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells

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Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer

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Mycosis fungoides and Sezary syndrome.

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12 December 2020

Expression of apoptosis markers on peripheral blood lymphocytes from patients with cutaneous T-cell lymphoma during extracorporeal photochemotherapy

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12 December 2020

Targeting STAT3 in cancer: how successful are we?

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12 December 2020

Emerging new therapies for cutaneous T-cell lymphoma

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12 December 2020

10.2478/S11658-010-0008-2

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275771&resulttype=core&format=json

Dimensions Publication ID

13 May 2020

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9 September 2019

https://scigraph.springernature.com/pub.10.2478/s11658-010-0008-2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275771&resulttype=core&format=json

13 May 2020

1 reference