SOCS3-mediated blockade of JAK/STAT3 signaling pathway reveals its major contribution to spinal cord neuroinflammation and mechanical allodynia after peripheral nerve injury (Q39712224)

From Wikidata

Jump to navigation Jump to search

scientific article published on April 2010

Language	Label	Description	Also known as
English	SOCS3-mediated blockade of JAK/STAT3 signaling pathway reveals its major contribution to spinal cord neuroinflammation and mechanical allodynia after peripheral nerve injury	scientific article published on April 2010

Statements

scholarly article

1 reference

Europe PubMed Central

14 September 2017

SOCS3-mediated blockade of JAK/STAT3 signaling pathway reveals its major contribution to spinal cord neuroinflammation and mechanical allodynia after peripheral nerve injury (English)

1 reference

Europe PubMed Central

14 September 2017

0 references

author name string

Elisa Dominguez

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

Annie Mauborgne

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

Jacques Mallet

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

Mathieu Desclaux

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

Michel Pohl

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

language of work or name

0 references

publication date

1 April 2010

1 reference

Europe PubMed Central

14 September 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

30

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

5754-5766

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

16

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6632340/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Detection of static and dynamic components of mechanical allodynia in rat models of neuropathic pain: are they signalled by distinct primary sensory neurones?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine signaling in the brain: putting a SOCS in it?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase of nociceptive threshold induced by intrathecal injection of interleukin-1beta in normal and carrageenan inflammatory rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of gp130-related Cytokines and Activation of JAK2/STAT3 Pathway in Astrocytes Precedes Up-regulation of Glial Fibrillary Acidic Protein in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Model of Neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the immune system in chronic pain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokines, chemokine receptors and pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of JAK/STAT signalling in neurons following spinal cord injury in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT3 as a downstream mediator of Trk signaling and functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lentiviral-mediated targeted NF-kappaB blockade in dorsal spinal cord glia attenuates sciatic nerve injury-induced neuropathic pain in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pin1 is required for the Ser727 phosphorylation-dependent Stat3 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lentiviral-mediated targeted transgene expression in dorsal spinal cord glia: tool for the study of glial cell implication in mechanisms underlying chronic pain development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropathic pain triad: neurons, immune cells and glia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine signaling modules in inflammatory responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do glial cells control pain?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCL2 is a key mediator of microglia activation in neuropathic pain states

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential implication of proinflammatory cytokine interleukin-6 in the development of cephalic versus extracephalic neuropathic pain in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor receptor 1 induces interleukin-6 upregulation through NF-kappaB in a rat neuropathic pain model

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathological and protective roles of glia in chronic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinal leptin contributes to the pathogenesis of neuropathic pain in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 induces microglial CX3CR1 expression in the spinal cord after peripheral nerve injury through the activation of p38 MAPK

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further evidence for 'pain-related' behaviours in a model of unilateral peripheral mononeuropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient analysis of experimental observations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative assessment of tactile allodynia in the rat paw

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor-kappa B p65 mediates the assembly and activation of the TNF-responsive element of the murine monocyte chemoattractant-1 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20410127

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5007-09.2010

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6632340&resulttype=core&format=json

15 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39712224&oldid=2089083983"