Partial depletion of CREB-binding protein reduces life expectancy in a mouse model of Huntington disease. (Q39706773)

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1 February 2020

title

Partial depletion of CREB-binding protein reduces life expectancy in a mouse model of Huntington disease (English)

1 reference

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1 February 2020

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0 references

2

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1 February 2020

author name string

Alexandra M Klevytska

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20448484%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Alena V Savonenko

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20448484%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

David R Borchelt

series ordinal

4

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1 February 2020

publication date

1 April 2010

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Journal of Neuropathology & Experimental Neurology

1 February 2020

published in

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1 February 2020

volume

69

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1 February 2020

issue

4

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1 February 2020

page(s)

396-404

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 February 2020

cites work

1 reference

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Huntington disease and the related disorder, dentatorubral-pallidoluysian atrophy (DRPLA).

21 January 2018

1 reference

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The hunt for huntingtin function: interaction partners tell many different stories

21 January 2018

1 reference

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Huntingtin-protein interactions and the pathogenesis of Huntington's disease

21 January 2018

1 reference

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Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

21 January 2018

1 reference

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Ca(2+)/CREB/CBP-dependent gene regulation: a shared mechanism critical in long-term synaptic plasticity and neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

21 January 2018

1 reference

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Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

21 January 2018

1 reference

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Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease

21 January 2018

1 reference

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Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300

21 January 2018

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Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

21 January 2018

1 reference

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Distinct behavioral and neuropathological abnormalities in transgenic mouse models of HD and DRPLA.

21 January 2018

1 reference

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Characterization of huntingtin pathologic fragments in human Huntington disease, transgenic mice, and cell models.

21 January 2018

1 reference

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Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein

21 January 2018

1 reference

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Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

CRE-mediated transcription is increased in Huntington's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Environmental enrichment slows disease progression in R6/2 Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Huntingtin inclusions do not deplete polyglutamine-containing transcription factors in HD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Neuronal intranuclear inclusions and neuropil aggregates in HdhCAG(150) knockin mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Toward understanding the molecular pathology of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E3181D6C436

10.1097/NEN.0B013E3181D6C436

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20448484%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference