Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia. (Q39653305)

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14 February 2020

title

Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia (English)

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14 February 2020

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1

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14 February 2020

Elisabetta Falcieri

6

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14 February 2020

James A. McCubrey

10

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author name string

Francesca Ricci

2

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14 February 2020

Pierluigi Tazzari

3

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14 February 2020

Francesca Chiarini

4

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14 February 2020

Michela Battistelli

5

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14 February 2020

Andrea Ognibene

7

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Pasqualepaolo Pagliaro

8

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Lucio Cocco

9

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14 February 2020

Alberto M Martelli

11

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publication date

1 March 2011

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Journal of Cellular Physiology

14 February 2020

number of pages

10

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based on heuristic

inferred from page(s)

published in

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volume

226

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page(s)

822-831

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14 February 2020

issue

3

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The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane

14 February 2020

cites work

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PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells

21 January 2018

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Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

1 reference

The minimal instrumentation requirements for Hoechst side population analysis: stem cell analysis on low-cost flow cytometry platforms

21 January 2018

1 reference

The Akt/PKB pathway: molecular target for cancer drug discovery

21 January 2018

1 reference

The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism

21 January 2018

1 reference

Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2.

21 January 2018

1 reference

Surface and inner cell behaviour along skeletal muscle cell in vitro differentiation

21 January 2018

1 reference

21 January 2018

It's T-ALL about Notch

1 reference

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

21 January 2018

1 reference

Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy

21 January 2018

1 reference

Perifosine: update on a novel Akt inhibitor.

21 January 2018

1 reference

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells

21 January 2018

1 reference

Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle

21 January 2018

1 reference

mTOR regulation of autophagy

21 January 2018

1 reference

The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group

21 January 2018

1 reference

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

Targeting the phosphoinositide 3-kinase pathway in cancer

21 January 2018

1 reference

Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

21 January 2018

1 reference

Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency.

21 January 2018

1 reference

Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia

21 January 2018

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Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms

21 January 2018

1 reference

Akt signaling regulates side population cell phenotype via Bcrp1 translocation.

21 January 2018

1 reference

Side-population cells in luminal-type breast cancer have tumour-initiating cell properties, and are regulated by HER2 expression and signalling

21 January 2018

1 reference

Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells

21 January 2018

1 reference

The nuts and bolts of AGC protein kinases

21 January 2018

1 reference

Acute lymphoblastic leukaemia

21 January 2018

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PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

21 January 2018

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Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy

21 January 2018

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Identification of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T-cell leukemia/lymphoma.

21 January 2018

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Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

21 January 2018

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PI3K pathway alterations in cancer: variations on a theme

21 January 2018

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Targeted therapy in T-cell malignancies: dysregulation of the cellular signaling pathways

21 January 2018

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Synergistic induction of apoptosis in human leukemia T cells by the Akt inhibitor perifosine and etoposide through activation of intrinsic and Fas-mediated extrinsic cell death pathways

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.22407

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14 February 2020

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