Novel cross-talk within the IKK family controls innate immunity (Q39622962)

13 September 2017

Novel cross-talk within the IKK family controls innate immunity (English)

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13 September 2017

Kristopher Clark

1

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13 September 2017

Mark Peggie

2

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13 September 2017

Lorna Plater

3

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13 September 2017

Ronald J Sorcek

4

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13 September 2017

Erick R R Young

5

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13 September 2017

Jeffrey B Madwed

6

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13 September 2017

Joanne Hough

7

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13 September 2017

Edward G McIver

8

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13 September 2017

Philip Cohen

9

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13 September 2017

language of work or name

English

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publication date

1 February 2011

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13 September 2017

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13 September 2017

434

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13 September 2017

93-104

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13 September 2017

1

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Regulation and function of IKK and IKK-related kinases

13 September 2017

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https://api.crossref.org/works/10.1042%2FBJ20101701

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

Essential function for the kinase TAK1 in innate and adaptive immune responses.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

Direct activation of protein kinases by unanchored polyubiquitin chains

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

Structural Basis for Recognition of Diubiquitins by NEMO

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

A ubiquitin ligase complex assembles linear polyubiquitin chains

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Pharmacologic inhibition of tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

The selectivity of protein kinase inhibitors: a further update

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

IkappaB kinase is an essential component of the Tpl2 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

In vivo identification of inducible phosphoacceptors in the IKKgamma/NEMO subunit of human IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

IKKi/IKKϵ Plays a Key Role in Integrating Signals Induced by Pro-inflammatory Stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Genomic structure and functional characterization of the promoter region of human IkappaB kinase-related kinase IKKi/IKKvarepsilon gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101701

IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101701

21 January 2018

Identifiers

DOI

10.1042/BJ20101701

1 reference

13 September 2017

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