Novel splice variants of human IKKε negatively regulate IKKε-induced IRF3 and NF-kB activation (Q39616594)

13 September 2017

Novel splice variants of human IKKε negatively regulate IKKε-induced IRF3 and NF-kB activation (English)

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13 September 2017

Anja Koop

1

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13 September 2017

Inga Lepenies

2

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13 September 2017

Oliver Braum

3

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13 September 2017

Parvin Davarnia

4

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13 September 2017

Gudrun Scherer

5

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13 September 2017

Helmut Fickenscher

6

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13 September 2017

Dieter Kabelitz

7

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13 September 2017

Sabine Adam-Klages

8

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13 September 2017

language of work or name

English

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publication date

3 December 2010

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European Journal of Immunology

13 September 2017

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13 September 2017

41

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13 September 2017

1

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13 September 2017

224-234

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Innate immunity to virus infection.

13 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Pattern recognition receptors and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

NAK is an IkappaB kinase-activating kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Triggering the interferon response: the role of IRF-3 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

IKK-i signals through IRF3 and NFkappaB to mediate the production of inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

IKKi/IKKϵ Plays a Key Role in Integrating Signals Induced by Pro-inflammatory Stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Inducible phosphorylation of NF-kappa B p65 at serine 468 by T cell costimulation is mediated by IKK epsilon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Inducible IkappaB kinase/IkappaB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kappaB activation in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Integrative genomic approaches identify IKBKE as a breast cancer oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Functional characterization of interferon regulatory factor 3a (IRF-3a), an alternative splice isoform of IRF-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Negative regulation of virus-triggered IFN-beta signaling pathway by alternative splicing of TBK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

RIP2-beta: a novel alternative mRNA splice variant of the receptor interacting protein kinase RIP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

Replication-competent rhabdoviruses with human immunodeficiency virus type 1 coats and green fluorescent protein: entry by a pH-independent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201040814

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7 January 2021

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Identifiers

DOI

10.1002/EJI.201040814

1 reference

13 September 2017

1 reference