Effect of mitochondrial dysfunction and oxidative stress on endogenous levels of coenzyme Q(10) in human cells (Q39594821)

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22 January 2020

title

Effect of mitochondrial dysfunction and oxidative stress on endogenous levels of coenzyme Q(10) in human cells (English)

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carbonyl cyanide p-trifluoromethoxyphenylhydrazone

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main subject

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ChEBI release 2020-05-28

1

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author name string

Feng-Yuan Chen

2

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Shih-Wei Chen

3

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Yu-Hsiang Huang

4

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Yun-Ru Chen

5

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Chih-Wei Chen

6

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publication date

9 February 2011

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Journal of Biochemical and Molecular Toxicology

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published in

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volume

25

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issue

5

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page(s)

280-289

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Metabolism and function of coenzyme Q.

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cites work

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Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject

21 January 2018

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Coenzyme Q--biosynthesis and functions

21 January 2018

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Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans

21 January 2018

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A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: a potentially treatable form of mitochondrial disease

21 January 2018

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Coenzyme Q10 is frequently reduced in muscle of patients with mitochondrial myopathy

21 January 2018

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A dynamic machinery for import of mitochondrial precursor proteins

21 January 2018

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Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines.

21 January 2018

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The role of mitochondria in pharmacotoxicology: a reevaluation of an old, newly emerging topic.

21 January 2018

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Mitochondria, oxygen free radicals, disease and ageing

21 January 2018

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The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice

21 January 2018

1 reference

Redox-based regulation of signal transduction: principles, pitfalls, and promises

21 January 2018

1 reference

Mitochondrial signaling pathways: a receiver/integrator organelle

21 January 2018

1 reference

Diseases of the mitochondrial DNA.

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Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage.

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The interaction of highly active uncouplers with mitochondria

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Cytoplasmic transfer of the mtDNA nt 8993 T-->G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio

21 January 2018

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Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

21 January 2018

1 reference

Isolation of human cell lines lacking mitochondrial DNA.

21 January 2018

1 reference

Increase of lipid peroxidation by cisplatin in WI38 cells but not in SV40-transformed WI38 cells.

21 January 2018

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Oxidative stress and upregulation of mitochondrial biogenesis genes in mitochondrial DNA-depleted HeLa cells

21 January 2018

1 reference

Cellular aging of mitochondrial DNA-depleted cells

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Enhancement of cisplatin-induced apoptosis and caspase 3 activation by depletion of mitochondrial DNA in a human osteosarcoma cell line.

21 January 2018

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Evaluation of the probes 2′,7′-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation

21 January 2018

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Impurities from polypropylene microcentrifuge tubes as a potential source of interference in simultaneous analysis of multiple lipid-soluble antioxidants by HPLC with electrochemical detection.

21 January 2018

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Mitochondrial uncoupling proteins--what is their physiological role?

21 January 2018

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Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis

21 January 2018

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Investigation of coenzyme Q biosynthesis in human fibroblast and HepG2 cells

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Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis.

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Mitochondria as key components of the stress response

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Mitochondrial-nuclear communications

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ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency

21 January 2018

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The evidence basis for coenzyme Q therapy in oxidative phosphorylation disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JBT.20387

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22 January 2020

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