The role of mitochondria in pharmacotoxicology: a reevaluation of an old, newly emerging topic. (Q36809514)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17475665%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

review article

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title

The role of mitochondria in pharmacotoxicology: a reevaluation of an old, newly emerging topic (English)

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30 December 2019

2

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30 December 2019

author name string

Roberto Scatena

1

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30 December 2019

Giorgia Botta

3

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30 December 2019

Giuseppe E Martorana

4

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30 December 2019

Bruno Giardina

5

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30 December 2019

publication date

2 May 2007

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American Journal of Physiology - Cell Physiology

30 December 2019

published in

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30 December 2019

volume

293

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30 December 2019

page(s)

C12-21

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30 December 2019

issue

1

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Isoniazid overdose: four case reports and review of the literature

30 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondria-derived oxidative stress induces a heat shock protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Genistein induces apoptosis in T lymphoma cells via mitochondrial damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

The SDH mutation database: an online resource for succinate dehydrogenase sequence variants involved in pheochromocytoma, paraganglioma and mitochondrial complex II deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Targeting dinitrophenol to mitochondria: limitations to the development of a self-limiting mitochondrial protonophore

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondria: pharmacological manipulation of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondrial mutations in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Fenofibrate impairs rat mitochondrial function by inhibition of respiratory complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on membrane potential and reactive oxygen species production in isolated piglet mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Semitelechelic HPMA copolymers functionalized with triphenylphosphonium as drug carriers for membrane transduction and mitochondrial localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Nitric oxide, complex I, and the modulation of mitochondrial reactive species in biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Proteasome inhibitors potentiate etoposide-induced cell death in human astrocytoma cells bearing a mutated p53 isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Coenzyme Q cytoprotective mechanisms for mitochondrial complex I cytopathies involves NAD(P)H: quinone oxidoreductase 1(NQO1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondrial abnormalities in HIV-infected lipoatrophic patients treated with antiretroviral agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Biotechnological production and applications of coenzyme Q10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

In AML Cell Lines Ara-C Combined with Purine Analogues is Able to Exert Synergistic as Well as Antagonistic Effects on Proliferation, Apoptosis and Disruption of Mitochondrial Membrane Potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Effect of nucleoside reverse transcriptase inhibitors on mitochondrial DNA synthesis in rats and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Is the sarcolemmal or mitochondrial K(ATP) channel activation important in the antiarrhythmic and cardioprotective effects during acute ischemia/reperfusion in the intact anesthetized rabbit model?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Drugs targeting mitochondrial functions to control tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Donor heart preservation with pinacidil: the role of the mitochondrial K ATP channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

2-Methoxyestradiol induces apoptosis in Ewing sarcoma cells through mitochondrial hydrogen peroxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondria as cancer drug targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

K+-independent actions of diazoxide question the role of inner membrane KATP channels in mitochondrial cytoprotective signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondria in health and disease: perspectives on a new mitochondrial biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Neurodegeneration and neuroprotection in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondrial involvement in nitric oxide-induced cellular death in cortical neurons in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Hydroxymethylglutaryl-CoA reductase inhibitors in older persons with acute myocardial infarction: evidence for an age-statin interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondrial tumour suppressors: a genetic and biochemical update

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

K(ATP) channels and preconditioning: a re-examination of the role of mitochondrial K(ATP) channels and an overview of alternative mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

K(ATP) channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondrial uncoupling as a target for drug development for the treatment of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

The mitochondrial electron transport and oxidative phosphorylation system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Suppression of human tumor cell proliferation through mitochondrial targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Cyclosporin A regulates the levels of cyclophilin A in neuroblastoma cells in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Effect of molecular structure on the performance of triarylmethane dyes as therapeutic agents for photochemical purging of autologous bone marrow grafts from residual tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Effect of nicorandil on coronary events in patients with stable angina: the Impact Of Nicorandil in Angina (IONA) randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudine- and zidovudine-containing regimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Evidence that the blockade of mitochondrial respiration by the neurotoxin 1-methyl-4-phenylpyridinium (MPP+) involves binding at the same site as the respiratory inhibitor, rotenone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Protective effect of metronidazole on uncoupling mitochondrial oxidative phosphorylation induced by NSAID: a new mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

New insights into structure and function of mitochondria and their role in aging and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondrial toxicity of nrti antiviral drugs: an integrated cellular perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Roles of skeletal muscle and peroxisome proliferator-activated receptors in the development and treatment of obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mechanisms of mitochondrial apoptosis induced by peripheral benzodiazepine receptor ligands in human colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Nutritional cofactor treatment in mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Dose-dependent inhibition of mitochondrial ATP synthase by 17 beta-estradiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Does nitric oxide modulate mitochondrial energy generation and apoptosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Inhibition and uncoupling of oxidative phosphorylation by nonsteroidal anti-inflammatory drugs: study in mitochondria, submitochondrial particles, cells, and whole heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Drug delivery to mitochondria: the key to mitochondrial medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Myocardial K(ATP) channels in preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Therapeutic effect of tamoxifen and energy-modulating vitamins on carbohydrate-metabolizing enzymes in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Nitric oxide and peroxynitrite interactions with mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

The mitochondrial myopathy encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Nitric oxide donor drugs: an update on pathophysiology and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: biochemical and pharmacological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Bezafibrate Induces a Mitochondrial Derangement in Human Cell Lines: A PPAR-Independent Mechanism for a Peroxisome Proliferator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondrial dysfunction by synthetic ligands of peroxisome proliferator activated receptors (PPARs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Evaluation of ubiquinone concentration and mitochondrial function relative to cerivastatin-induced skeletal myopathy in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Modulation of TCA cycle enzymes and electron transport chain systems in experimental lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Effects of menadione and its derivative on cultured cardiomyocytes with mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Antidiabetic sulphonylureas activate mitochondrial permeability transition in rat skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Delivery of bioactive molecules to mitochondria in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Identification of a potentially neurotoxic pyridinium metabolite of haloperidol in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondria as a pharmacological target

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Effects of cisplatin on mitochondrial function in Jurkat cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondria as we don't know them

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Valproic acid II: effects on oxidative stress, mitochondrial membrane potential, and cytotoxicity in glutathione-depleted rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Concentration dependent mitochondrial effect of amiodarone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Mitochondrial targets of drug toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Doxorubicin-induced cardiac mitochondrionopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Dual roles of mitochondrial K(ATP) channels in diazoxide-mediated protection in isolated rabbit hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

Potential use of alexidine dihydrochloride as an apoptosis-promoting anticancer agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

21 January 2018

Mitochondrial disorders

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00314.2006

10.1152/AJPCELL.00314.2006

21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17475665%20AND%20SRC:MED&resulttype=core&format=json

release_44ngj6vscvfsldvvpdjqea2fha

30 December 2019

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mapped directly with Wikidata item

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based on heuristic

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