Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes (Q39540927)

12 September 2017

1 reference

title

Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes (English)

1 reference

12 September 2017

Lock EA

1

1 reference

PubMed ID

3056657

12 September 2017

language of work or name

English

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publication date

1 January 1988

1 reference

Critical Reviews in Toxicology

12 September 2017

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12 September 2017

19

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12 September 2017

23-42

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12 September 2017

1

1 reference

Chemically induced nephrotoxicity: role of metabolic activation

12 September 2017

1 reference

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The metabolism and nephrotoxicity of tetrafluoroethylene in the rat.

21 January 2018

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The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium I. Activation through conjugation with glutathion in vitro

21 January 2018

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The role of glutathione conjugation in the mutagenicity of 1,2-dibromoethane.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408448809040816

Evidence for formation of an S-[2-(N7-guanyl)ethyl]glutathione adduct in glutathione-mediated binding of the carcinogen 1,2-dibromoethane to DNA.

21 January 2018

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Cellular effects of reactive intermediates: nephrotoxicity of S-conjugates of amino acids

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408448809040816

Chronic toxicity and reproduction studies of hexachlorobutadiene in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Short-term toxicity and reproduction studies in rats with hexachloro-(1,3)-butadiene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Effects of hexachlorobutadiene (HCBD) on renal function and renal organic ion transport in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity

21 January 2018

1 reference

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The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells

21 January 2018

1 reference

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Isolation of anthglutin, an inhibitor of γ-glutamyl transpeptidase from Penicillum oxalicum

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

The formation and biotransformation of cysteine conjugates of halogenated ethylenes by rabbit renal tubules

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Depletion by 1,2-dibromoethane, 1,2-dibromo-3-chloropropane, tris(2,3-dibromopropyl)phosphate, and hexachloro-1,3-butadiene of reduced non-protein sulfhydryl groups in target and non-target organs.

21 January 2018

1 reference

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Nephrotoxicity of hexachlorobutadiene and its glutathione-derived conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: a possible explanation for its nephrocarcinogenicity in male rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

The metabolism of S-(1,2 Dichlorovinyl)-l-cysteine by rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Structure/activity studies of the nephrotoxic and mutagenic action of cysteine conjugates of chloro- and fluoroalkenes

21 January 2018

1 reference

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Purification and characterization of human hepatic cysteine-conjugate beta-lyase

21 January 2018

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Studies on the GABA pathway. I. The inhibition of gamma-aminobutyric acid-alpha-ketoglutaric acid transaminase in vitro and in vivo by U-7524 (amino-oxyacetic acid).

21 January 2018

1 reference

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Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Effect of halogenated vinyl cysteine conjugates on renal tubular active transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

A mechanism of S-(1,2,3,4,4-pentachloro-1,3-butadienyl)-L-cysteine toxicity to rabbit renal proximal tubules

21 January 2018

1 reference

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Metabolic activation and detoxication of nephrotoxic cysteine and homocysteine S-conjugates

21 January 2018

1 reference

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Transport of N-acetyl-S-pentachloro-1,3-butadienylcysteine by rat renal cortex

21 January 2018

1 reference

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Correlation of the in vivo and in vitro renal toxicity of S-(1,2-dichlorovinyl)-L-cysteine

21 January 2018

1 reference

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Effect of the organic acid transport inhibitor probenecid on renal cortical uptake and proximal tubular toxicity of hexachloro-1,3-butadiene and its conjugates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Mercapturic acid formation is an activation and intermediary step in the metabolism of hexachlorobutadiene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Metabolic activation of chlorinated ethylenes: dependence of mutagenic effect on electrophilic reactivity of the metabolically formed epoxides

21 January 2018

1 reference

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Further studies on the site and mechanism of action of s-(1,2 dichlorovinyl)-l-systeine and s-(1,2 dichlorovinyl)-3-mercaptopropionic acid in rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Mutagenicity of hexachlorobutadiene, perchlorobutenoic acid and perchlorobutenoic acid chloride

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Mutagenicity of the mercapturic acid and other S-containing derivatives of hexachloro-1,3-butadiene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

Results of a two year chronic toxicity study with hexachlorobutadiene in rats

21 January 2018

1 reference

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Chronic kidney disease and organic chemical exposures: evaluations of causal relationships in humans and experimental animals

21 January 2018

1 reference

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Species differences in response to trichloroethylene. II. Biotransformation in rats and mice.

21 January 2018

1 reference

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Urinary enzymes and protein patterns as indicators of injury to different regions of the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448809040816

10.3109/10408448809040816

21 January 2018

Identifiers

DOI

0 references

PubMed ID

3056657

1 reference

PubMed ID

3056657