An unbiased genome-wide analysis of zinc-finger nuclease specificity (Q39493921)

12 September 2017

An unbiased genome-wide analysis of zinc-finger nuclease specificity (English)

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12 September 2017

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16

Christof von Kalle

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Luigi Naldini

15

Luigi Naldini

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Pietro Genovese

Pietro Genovese

5

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Angelo Leone Lombardo

Angelo Lombardo

2

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Philip D Gregory

Philip D Gregory

12

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Manfred Schmidt

14

Manfred Schmidt

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12 September 2017

Richard Gabriel

1

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12 September 2017

Anne Arens

3

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12 September 2017

Jeffrey C Miller

4

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12 September 2017

Christine Kaeppel

6

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12 September 2017

Ali Nowrouzi

7

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12 September 2017

Cynthia C Bartholomae

8

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12 September 2017

Jianbin Wang

9

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12 September 2017

Geoffrey Friedman

10

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12 September 2017

Michael C Holmes

11

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12 September 2017

Hanno Glimm

13

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12 September 2017

7 August 2011

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12 September 2017

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12 September 2017

29

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12 September 2017

816-823

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12 September 2017

9

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https://scigraph.springernature.com/pub.10.1038/nbt.1948

12 September 2017

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cites work

Adeno-associated virus vectors integrate at chromosome breakage sites

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12 December 2020

Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection

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12 December 2020

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

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12 December 2020

BLAT—The BLAST-Like Alignment Tool

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12 December 2020

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

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12 December 2020

Transient gene expression by nonintegrating lentiviral vectors

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12 December 2020

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

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12 December 2020

FokI dimerization is required for DNA cleavage

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12 December 2020

HIV-1 integration in the human genome favors active genes and local hotspots

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12 December 2020

FokI requires two specific DNA sites for cleavage

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12 December 2020

Distinct factors control histone variant H3.3 localization at specific genomic regions

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12 December 2020

Targeted genome modifications using integrase-deficient lentiviral vectors.

1 reference

12 December 2020

Mutations in the human immunodeficiency virus type 1 integrase D,D(35)E motif do not eliminate provirus formation.

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12 December 2020

Genome editing with engineered zinc finger nucleases

1 reference

12 December 2020

Expanding or restricting the target site repertoire of zinc-finger nucleases: the inter-domain linker as a major determinant of target site selectivity

1 reference

12 December 2020

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

1 reference

12 December 2020

Non-homologous end-joining for repairing I-SceI-induced DNA double strand breaks in human cells

1 reference

12 December 2020

An improved zinc-finger nuclease architecture for highly specific genome editing

1 reference

12 December 2020

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

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12 December 2020

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

1 reference

12 December 2020

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

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12 December 2020

A rapid and general assay for monitoring endogenous gene modification

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12 December 2020

Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells

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12 December 2020

Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk

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12 December 2020

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

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12 December 2020

Basic local alignment search tool

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12 December 2020

Promiscuous patching of broken chromosomes in mammalian cells with extrachromosomal DNA.

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12 December 2020

Knockout rats via embryo microinjection of zinc-finger nucleases

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12 December 2020

High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR).

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12 December 2020

Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing

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12 December 2020

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

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12 December 2020

Capture of DNA sequences at double-strand breaks in mammalian chromosomes

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12 December 2020

Comprehensive genomic access to vector integration in clinical gene therapy

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12 December 2020

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

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12 December 2020

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

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12 December 2020

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

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12 December 2020

Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage

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12 December 2020

Novel integrase-defective lentiviral episomal vectors for gene transfer

1 reference

12 December 2020

Frequent endonuclease cleavage at off-target locations in vivo.

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12 December 2020

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

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12 December 2020

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

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12 December 2020

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

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12 December 2020

The discovery of zinc fingers and their applications in gene regulation and genome manipulation.

1 reference

12 December 2020

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

1 reference

12 December 2020

Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases.

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12 December 2020

Identifiers

DOI

10.1038/NBT.1948

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Dimensions Publication ID

12 September 2017

1033698278

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Fatcat ID

release_fnpauh4q3fahdp5s7g45kio3gq

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1 reference