Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer (Q39466612)

12 September 2017

Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer (English)

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Zhixiang Wu

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Jessica B Doondeea

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Amin Moghaddas Gholami

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Melanie C Janning

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Simone Lemeer

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Karl Kramer

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Suzanne A Eccles

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Reidar Grenman

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Axel Walch

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Stephan M Feller

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language of work or name

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28 September 2011

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Molecular & Cellular Proteomics

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M111.011635

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describes a project that uses

12 September 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3237086/fullTextXML

inferred from PubMed Central ID database lookup

limma

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22 June 2022

https://europepmc.org/article/PMC/3237086

inferred from PubMed Central ID database lookup

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival

14 September 2017

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EphA2 as a novel molecular marker and target in glioblastoma multiforme

14 September 2017

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Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts

14 September 2017

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Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection

14 September 2017

1 reference

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Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells

25 September 2017

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Relation of DNA ploidy and proliferation rate to radiation sensitivity in squamous carcinoma cell lines

25 September 2017

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Addressing accuracy and precision issues in iTRAQ quantitation

25 September 2017

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Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation

17 June 2018

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17 June 2018

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Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas

17 June 2018

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Two new human tumor cell lines derived from squamous cell carcinomas of the tongue: establishment, characterization and response to cytotoxic treatment.

17 June 2018

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Effects of radiation fractionation on four squamous cell carcinoma lines with dissimilar inherent radiation sensitivity

17 June 2018

1 reference

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Frequent p53 mutations in head and neck cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237086

A comparison of labeling and label-free mass spectrometry-based proteomics approaches.

17 June 2018

1 reference

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Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237086

Expression of EphA2 and VEGF in squamous cell carcinoma of the tongue: correlation with the angiogenesis and clinical outcome.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237086

Involvement of EphA2 in head and neck squamous cell carcinoma: mRNA expression, loss of heterozygosity and immunohistochemical studies

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237086

Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

21 August 2018

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Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage.

21 August 2018

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EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma

21 August 2018

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Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors.

21 August 2018

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A variant form of laminin is responsible for the neurite outgrowth-promoting activity in conditioned medium from a squamous carcinoma cell line

21 August 2018

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Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.

21 August 2018

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Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas

21 August 2018

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Claudin 1 overexpression increases invasion and is associated with aggressive histological features in oral squamous cell carcinoma

21 August 2018

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Proteomics-based strategies in kinase drug discovery

2 December 2018

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Differential Label-free Quantitative Proteomic Analysis ofShewanella oneidensisCultured under Aerobic and Suboxic Conditions by Accurate Mass and Time Tag Approach

2 December 2018

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Development of a new invasion and metastasis model of human oral squamous cell carcinomas

2 December 2018

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12 December 2020

A simple specific pattern of chromosomal aberrations at early stages of head and neck squamous cell carcinomas: PIK3CA but not p63 gene as a likely target of 3q26-qter gains

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12 December 2020

Mutation and downregulation of the transforming growth factor beta type II receptor gene in primary squamous cell carcinomas of the head and neck

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12 December 2020

Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis

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12 December 2020

Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck

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12 December 2020

PTEN mutations and proteus syndrome

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12 December 2020

A new grammar for drug discovery

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12 December 2020

Identifiers

DOI

10.1074/MCP.M111.011635

1 reference

release_ivenjb6bznbqlm4af35vauwuvu

12 September 2017

0 references

1 reference

12 September 2017

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