EphA2 as a target for ovarian cancer therapy (Q36318535)

13 August 2017

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title

EphA2 as a target for ovarian cancer therapy (English)

1 reference

13 August 2017

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Michael S Kinch

2

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Anil K. Sood

series ordinal

3

object named as

Anil K Sood

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13 August 2017

Charles N Landen

1

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PubMed ID

16300469

13 August 2017

language of work or name

English

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publication date

1 December 2005

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Expert Opinion on Therapeutic Targets

13 August 2017

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13 August 2017

9

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13 August 2017

1179-1187

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13 August 2017

6

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Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis

13 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Crystal structure of an Eph receptor-ephrin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Effects of overexpression of ephrin-B2 on tumour growth in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

EphB receptor activity suppresses colorectal cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

EphA2 expression is associated with aggressive features in ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Prognostic value of EphA2 and EphrinA-1 in squamous cell cervical carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Overexpression of the EphA2 tyrosine kinase in prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Electrophoretic analysis of proteins associated with tumor cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

The role of integrins in tumorigenesis and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

An ephrin mimetic peptide that selectively targets the EphA2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

B61 is a ligand for the ECK receptor protein-tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

LMW-PTP is a positive regulator of tumor onset and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Reduced expression of EphrinA1 (EFNA1) inhibits three-dimensional growth of HT29 colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Immunocompetent mouse model of breast cancer for preclinical testing of EphA2-targeted therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

siRNA therapeutics: big potential from small RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Unlocking the potential of the human genome with RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

RNA interference in adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

siRNA-mediated gene silencing in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Therapeutic potential of retroviral RNAi vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

siRNA relieves chronic neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Inhibition of respiratory viruses by nasally administered siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.6.1179

10.1517/14728222.9.6.1179

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16300469