An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence (Q39446297)

12 September 2017

An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence (English)

1 reference

12 September 2017

2

Karen H Vousden

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12 September 2017

1

Arnaud M Vigneron

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PMCID

3261561

12 September 2017

language of work or name

English

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publication date

8 November 2011

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12 September 2017

10

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inferred from page(s)

published in

The EMBO Journal

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12 September 2017

31

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12 September 2017

2

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12 September 2017

471-480

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PMCID

3261561

describes a project that uses

12 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3261561/fullTextXML

inferred from PubMed Central ID database lookup

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Metabolic regulation by p53.

12 September 2017

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iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway

12 September 2017

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PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

12 September 2017

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The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1

12 September 2017

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12 September 2017

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ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development

12 September 2017

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The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

12 September 2017

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12 September 2017

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TWISTing an embryonic transcription factor into an oncoprotein

12 September 2017

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Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive hepatocellular carcinoma

12 September 2017

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Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation

12 September 2017

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Blinded by the Light: The Growing Complexity of p53

12 September 2017

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Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds

12 September 2017

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TEAD mediates YAP-dependent gene induction and growth control

12 September 2017

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TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

12 September 2017

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RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

12 September 2017

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ASPP: a new family of oncogenes and tumour suppressor genes

12 September 2017

1 reference

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iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261561

ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth

12 September 2017

1 reference

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A novel human p53 isoform is an essential element of the ATR-intra-S phase checkpoint

12 September 2017

1 reference

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The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.

12 September 2017

1 reference

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ASPP1 and ASPP2 are new transcriptional targets of E2F

12 September 2017

1 reference

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Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F.

12 September 2017

1 reference

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ASPP1 and ASPP2: common activators of p53 family members

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261561

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261561

ASPP proteins specifically stimulate the apoptotic function of p53

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261561

12 September 2017

Surfing the p53 network

1 reference

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Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.

12 September 2017

1 reference

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ASPP2 regulates epithelial cell polarity through the PAR complex.

14 September 2017

1 reference

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Cellular quiescence caused by the Mdm2 inhibitor nutlin-3A.

14 September 2017

1 reference

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A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells

14 September 2017

1 reference

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Mutational Analysis of ASPP1 and ASPP2 Genes, a p53-related Gene, in Gastric and Cololorectal Cancers with Microsatellite Instability

14 September 2017

1 reference

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SUMO-modified nuclear cyclin D1 bypasses Ras-induced senescence

25 September 2017

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p53-Dependent p21 mRNA elongation is impaired when DNA replication is stalled.

17 June 2018

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Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells

17 June 2018

1 reference

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Insight into the structural basis of pro- and antiapoptotic p53 modulation by ASPP proteins

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261561

Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261561

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22068052

12 December 2020

inferred from PubMed ID database lookup

Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22068052

12 December 2020

inferred from PubMed ID database lookup

p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22068052

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/EMBOJ.2011.402

1 reference

12 September 2017

1 reference

12 September 2017

1 reference

PMCID

3261561