Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro (Q39375788)

11 September 2017

Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro (English)

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11 September 2017

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Min-Bin Chen

1

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11 September 2017

Xiao-Yang Wu

2

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11 September 2017

Guo-Qing Tao

3

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11 September 2017

Chao-Ying Liu

4

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11 September 2017

Jian Chen

5

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11 September 2017

Li-Qiang Wang

6

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11 September 2017

Pei-Hua Lu

7

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11 September 2017

language of work or name

English

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publication date

3 July 2012

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International Journal of Cancer

11 September 2017

12

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based on heuristic

inferred from page(s)

published in

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131

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11

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2487-2498

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Therapeutic potential of curcumin in gastrointestinal diseases

11 September 2017

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Chemopreventive properties of curcumin

21 January 2018

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Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells

21 January 2018

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Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R.

21 January 2018

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Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29.

21 January 2018

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Comparison of oxaliplatin- and curcumin-mediated antiproliferative effects in colorectal cell lines

21 January 2018

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Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.

21 January 2018

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Enriching lipid nanovesicles with short-chain glucosylceramide improves doxorubicin delivery and efficacy in solid tumors

21 January 2018

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Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis

21 January 2018

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The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism

21 January 2018

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Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells

21 January 2018

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c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL.

21 January 2018

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Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species

21 January 2018

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Co-administration of perifosine with paclitaxel synergistically induces apoptosis in ovarian cancer cells: more than just AKT inhibition

21 January 2018

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Activation of AMP-activated protein kinase contributes to doxorubicin-induced cell death and apoptosis in cultured myocardial H9c2 cells

21 January 2018

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Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell

21 January 2018

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Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells.

21 January 2018

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Curcumin synergizes with resveratrol to inhibit colon cancer.

21 January 2018

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Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway

21 January 2018

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Multiple molecular targets in cancer chemoprevention by curcumin

21 January 2018

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Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-kappaB signaling

21 January 2018

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Grifolin induces apoptosis via inhibition of PI3K/AKT signalling pathway in human osteosarcoma cells

21 January 2018

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C6 ceramide potentiates curcumin-induced cell death and apoptosis in melanoma cell lines in vitro

21 January 2018

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Coupling endoplasmic reticulum stress to the cell death program in mouse melanoma cells: effect of curcumin

21 January 2018

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

21 January 2018

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Synergistic role of curcumin with current therapeutics in colorectal cancer: minireview.

21 January 2018

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Elimination of Colon Cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX.

21 January 2018

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Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration

21 January 2018

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

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Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.27548

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11 September 2017

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