MicroRNA-21 expression is regulated by β-catenin/STAT3 pathway and promotes glioma cell invasion by direct targeting RECK. (Q39342199)

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2 February 2020

title

MicroRNA-21 expression is regulated by β-catenin/STAT3 pathway and promotes glioma cell invasion by direct targeting RECK (English)

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Lei Han

1

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Xiao Yue

2

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Xuan Zhou

3

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Feng-Ming Lan

4

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Gan You

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2 February 2020

Wei Zhang

6

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2 February 2020

Kai-Liang Zhang

7

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Chun-Zhi Zhang

8

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Jin-Quan Cheng

9

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Shi-Zhu Yu

10

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Pei-Yu Pu

11

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Tao Jiang

12

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Chun-Sheng Kang

13

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publication date

28 May 2012

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CNS Neuroscience & Therapeutics

2 February 2020

published in

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volume

18

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issue

7

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page(s)

573-583

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β-catenin and Gli1 are prognostic markers in glioblastoma.

2 February 2020

cites work

1 reference

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Gliomas display a microRNA expression profile reminiscent of neural precursor cells.

21 January 2018

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Stat3 activation is required for cellular transformation by v-src

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Recent developments in the molecular characterization and treatment of oligodendroglial tumors

21 January 2018

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12 December 2020

Molecular mechanisms of glioma invasiveness: the role of proteases

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12 December 2020

MicroRNAs: genomics, biogenesis, mechanism, and function

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12 December 2020

Wnt/beta-catenin-pathway as a molecular target for future anti-cancer therapeutics

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12 December 2020

MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

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12 December 2020

Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer

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12 December 2020

MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas

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12 December 2020

SMAD proteins control DROSHA-mediated microRNA maturation

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12 December 2020

MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators

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12 December 2020

beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma.

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12 December 2020

Experience with irinotecan for the treatment of malignant glioma

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12 December 2020

MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells

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12 December 2020

Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth

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12 December 2020

MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G.

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12 December 2020

miR-21: a small multi-faceted RNA.

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12 December 2020

MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme

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12 December 2020

Wnt/beta-catenin signaling: components, mechanisms, and diseases

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12 December 2020

Identification and functional characterization of microRNAs involved in the malignant progression of gliomas

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12 December 2020

Antiangiogenic therapies for high-grade glioma

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12 December 2020

Tat-BMPs-PAMAM conjugates enhance therapeutic effect of small interference RNA on U251 glioma cells in vitro and in vivo.

1 reference

12 December 2020

The modulation of microRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma

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12 December 2020

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

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12 December 2020

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

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12 December 2020

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

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12 December 2020

Radiation-induced micro-RNA modulation in glioblastoma cells differing in DNA-repair pathways

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12 December 2020

Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma

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12 December 2020

Genetic variation in microRNA networks: the implications for cancer research

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12 December 2020

AKT2 expression is associated with glioma malignant progression and required for cell survival and invasion.

1 reference

12 December 2020

Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3.

1 reference

12 December 2020

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

1 reference

12 December 2020

Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells

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12 December 2020

Genome-wide expression profiling identifies deregulated miRNAs in malignant astrocytoma.

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12 December 2020

IFN induces miR-21 through a signal transducer and activator of transcription 3-dependent pathway as a suppressive negative feedback on IFN-induced apoptosis.

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12 December 2020

MicroRNA roles in beta-catenin pathway

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12 December 2020

Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of β-catenin-mediated transcription

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12 December 2020

Interruption of β-catenin suppresses the EGFR pathway by blocking multiple oncogenic targets in human glioma cells.

1 reference

12 December 2020

10.1111/J.1755-5949.2012.00344.X

Identifiers

DOI

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