Molecular mechanisms of glioma invasiveness: the role of proteases (Q35166808)

6 August 2017

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title

Molecular mechanisms of glioma invasiveness: the role of proteases (English)

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6 August 2017

neoplastic invasiveness

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1

Jasti S Rao

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PubMed ID

12835669

6 August 2017

language of work or name

English

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publication date

1 July 2003

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6 August 2017

Nature Reviews Cancer

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6 August 2017

3

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6 August 2017

489-501

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6 August 2017

7

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https://scigraph.springernature.com/pub.10.1038/nrc1121

6 August 2017

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cites work

Age and radiation response in glioblastoma multiforme.

1 reference

Some observations on the localization of hyaluronic acid in adult, newborn and embryonal rat brain

21 January 2018

1 reference

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

21 January 2018

1 reference

Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis

21 January 2018

1 reference

uPAR: a versatile signalling orchestrator

21 January 2018

1 reference

The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R.

21 January 2018

1 reference

Production of urokinase-type plasminogen activator (u-PA) and plasminogen activator inhibitor-1 (PAI-1) in human brain tumours.

21 January 2018

1 reference

Expression and localisation of urokinase-type plasminogen activator gene in gliomas.

21 January 2018

1 reference

Direct binding of occupied urokinase receptor (uPAR) to LDL receptor-related protein is required for endocytosis of uPAR and regulation of cell surface urokinase activity

21 January 2018

1 reference

Expression and cellular localization of low-density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor in human glioblastoma in vivo.

21 January 2018

1 reference

Up-regulation of urokinase-type plasminogen activator and its receptor correlates with enhanced invasion activity of human glioma cells mediated by transforming growth factor-alpha or basic fibroblast growth factor

21 January 2018

1 reference

Urokinase antisense oligodeoxynucleotides as a novel therapeutic agent for malignant glioma: in vitro and in vivo studies of uptake, effects and toxicity

21 January 2018

1 reference

Inhibitory effects of phenylbutyrate on the proliferation, morphology, migration and invasiveness of malignant glioma cells.

21 January 2018

1 reference

A peptide derived from the non-receptor-binding region of urokinase plasminogen activator inhibits glioblastoma growth and angiogenesis in vivo in combination with cisplatin

21 January 2018

1 reference

Modulation of invasive properties of human glioblastoma cells stably expressing amino-terminal fragment of urokinase-type plasminogen activator.

21 January 2018

1 reference

In vitro inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor

21 January 2018

1 reference

Inhibition of in vivo tumorigenicity and invasiveness of a human glioblastoma cell line transfected with antisense uPAR vectors

21 January 2018

1 reference

Altered in vitro spreading and cytoskeletal organization in human glioma cells by downregulation of urokinase receptor

21 January 2018

1 reference

Urokinase induces receptor mediated brain tumor cell migration and invasion.

21 January 2018

1 reference

High-molecular-weight serum protein complexes differentially promote cell migration and the focal adhesion localization of the urokinase receptor in human glioma cells.

21 January 2018

1 reference

Downregulation of urokinase-type plasminogen activator receptor (uPAR) induces caspase-mediated cell death in human glioblastoma cells

21 January 2018

1 reference

The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts

21 January 2018

1 reference

Down-regulation of integrin alpha(v)beta(3) expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense urokinase-type plasminogen activator receptor (uPAR) and sense p16 genes.

21 January 2018

1 reference

Suppression of glioma invasion and growth by adenovirus-mediated delivery of a bicistronic construct containing antisense uPAR and sense p16 gene sequences

21 January 2018

1 reference

Targeting urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT.

21 January 2018

1 reference

3-Amidinophenylalanine-based inhibitors of urokinase

21 January 2018

1 reference

Time and dose dependency of the suppression of pulmonary metastases of rat mammary cancer by amiloride.

21 January 2018

1 reference

High-affinity urokinase-derived cyclic peptides inhibiting urokinase/urokinase receptor-interaction: effects on tumor growth and spread

21 January 2018

1 reference

Collagenase: a key enzyme in collagen turnover

21 January 2018

1 reference

Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites

21 January 2018

1 reference

Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factors

21 January 2018

1 reference

Induction of matrix metalloproteinase-9 requires a polymerized actin cytoskeleton in human malignant glioma cells.

21 January 2018

1 reference

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

21 January 2018

1 reference

In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy

21 January 2018

1 reference

How matrix metalloproteinases regulate cell behavior

21 January 2018

1 reference

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

21 January 2018

1 reference

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

21 January 2018

1 reference

Modulation of endothelial cell morphogenesis in vitro by MMP-9 during glial-endothelial cell interactions.

21 January 2018

1 reference

Roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the signal transduction of basic fibroblast growth factor in endothelial cells during angiogenesis

21 January 2018

1 reference

Matrix metalloproteinases: they're not just for matrix anymore!

21 January 2018

1 reference

Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape

21 January 2018

1 reference

Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas

21 January 2018

1 reference

Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.

21 January 2018

1 reference

Elevated levels of Mr 92,000 type IV collagenase during tumor growth in vivo.

21 January 2018

1 reference

Regulation of MMP-9 (type IV collagenase) production and invasiveness in gliomas by the extracellular signal-regulated kinase and jun amino-terminal kinase signaling cascades

21 January 2018

1 reference

Adenovirus-mediated expression of antisense MMP-9 in glioma cells inhibits tumor growth and invasion.

21 January 2018

1 reference

Inhibition of Wilms' tumor growth by intramuscular administration of tissue inhibitor of metalloproteinases-4 plasmid DNA.

21 January 2018

1 reference

Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using an in vitro matrigel model

21 January 2018

1 reference

TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis

21 January 2018

1 reference

TIMP-2 is required for efficient activation of proMMP-2 in vivo

21 January 2018

1 reference

Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomas in vitro.

21 January 2018

1 reference

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

21 January 2018

1 reference

An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression

21 January 2018

1 reference

Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro

21 January 2018

1 reference

Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.

21 January 2018

1 reference

Functional overlap between two classes of matrix-degrading proteases in wound healing

21 January 2018

1 reference

The role of integrin receptors in aspects of glioma invasion in vitro.

21 January 2018

1 reference

Modulation of matrix metalloprotease-2 and invasion in human glioma cells by alpha 3 beta 1 integrin.

21 January 2018

1 reference

Evaluation of the effects of swainsonine, captopril, tangeretin and nobiletin on the biological behaviour of brain tumour cells in vitro

21 January 2018

1 reference

The structure of the mouse cathepsin B gene and its putative promoter

21 January 2018

1 reference

Cathepsin B activity in human lung tumor cell lines: ultrastructural localization, pH sensitivity, and inhibitor status at the cellular level

21 January 2018

1 reference

Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B.

21 January 2018

1 reference

Further studies on the activation of procollagenase, the latent precursor of bone collagenase. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation

21 January 2018

1 reference

Secretion of cathepsin B by human gliomas in vitro.

21 January 2018

1 reference

Overexpression and localization of cathepsin B during the progression of human gliomas.

21 January 2018

1 reference

Immunolocalization of cathepsin B in human glioma: implications for tumor invasion and angiogenesis

21 January 2018

1 reference

Cathepsin B and glioma invasion

21 January 2018

1 reference

Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells.

21 January 2018

1 reference

Expression of cysteine protease inhibitors in human gliomas and meningiomas

21 January 2018

1 reference

Cathepsin B and its inhibitor stefin A in brain tumors.

21 January 2018

1 reference

Modulation of cystatin C expression impairs the invasive and tumorigenic potential of human glioblastoma cells.

21 January 2018

1 reference

Biological mechanisms of glioma invasion and potential therapeutic targets

21 January 2018

1 reference

Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

21 January 2018

1 reference

ECM-mediated glioma cell invasion.

21 January 2018

1 reference

The extracellular matrix of the central and peripheral nervous systems: structure and function

21 January 2018

1 reference

Immunocytochemical localization of a chondroitin sulfate proteoglycan in nervous tissue. II. Studies in developing brain

21 January 2018

1 reference

A synaptic vesicle antigen is restricted to the junctional region of the presynaptic plasma membrane

21 January 2018

1 reference

Proteoglycans and neoplastic—mesenchymal cell interactions

21 January 2018

1 reference

Topographic anatomy and CT correlations in the untreated glioblastoma multiforme.

21 January 2018

1 reference

Immunohistochemical localization of extracellular matrix proteins in human glioma, both in vivo and in vitro.

21 January 2018

1 reference

New perspectives in cell adhesion: RGD and integrins

21 January 2018

1 reference

Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells

21 January 2018

1 reference

The role of extracellular matrix in human astrocytoma migration and proliferation studied in a microliter scale assay.

21 January 2018

1 reference

Multiple integrins mediate cell attachment to cytotactin/tenascin

21 January 2018

1 reference

Stimulation of angiogenesis through cathepsin B inactivation of the tissue inhibitors of matrix metalloproteinases

21 January 2018

1 reference

Plasminogen activators catalyse conversion of inhibitor from fibrosarcoma cells to an inactive form with a lower apparent molecular mass

21 January 2018

1 reference

Urokinase regulates vitronectin binding by controlling urokinase receptor oligomerization

31 March 2020

1 reference

Regulation of matrix metalloproteinase expression in tumor invasion.

31 March 2020

1 reference

Experimental metastasis is suppressed in MMP-9-deficient mice

31 March 2020

1 reference

Matrix metalloprotease-9 release from monocytes increases as a function of differentiation: implications for neuroinflammation and neurodegeneration

31 March 2020

1 reference

Transfection of an invasive human astrocytoma cell line with a TIMP-1 cDNA: modulation of astrocytoma invasive potential.

31 March 2020

1 reference

Vascular endothelial growth factor tightly regulates in vivo development of murine hepatocellular carcinoma cells

31 March 2020

1 reference

Wild type and mutant p53 differentially regulate the gene expression of human collagenase-3 (hMMP-13)

31 March 2020

1 reference

Transcription of human cathepsin B is mediated by Sp1 and Ets family factors in glioma

31 March 2020

1 reference

Functional analysis of cathepsin B-like cysteine proteases from Leishmania donovani complex. Evidence for the activation of latent transforming growth factor beta

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRC1121

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6 August 2017

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PubMed ID

12835669