Prognostic implications of mutations in NOTCH1 and FBXW7 in childhood T-ALL treated according to the NOPHO ALL-1992 and ALL-2000 protocols (Q39272383)

10 September 2017

Prognostic implications of mutations in NOTCH1 and FBXW7 in childhood T-ALL treated according to the NOPHO ALL-1992 and ALL-2000 protocols (English)

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10 September 2017

Sofie Degerman

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Jonas Abrahamsson

object named as

Jonas Abrahamsson

14

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author name string

Linda Fogelstrand

1

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10 September 2017

Anna Staffas

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10 September 2017

Carina Wasslavik

3

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10 September 2017

Helene Sjögren

4

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10 September 2017

Stefan Söderhäll

5

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10 September 2017

Britt-Marie Frost

6

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10 September 2017

Erik Forestier

7

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10 September 2017

Mikael Behrendtz

9

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10 September 2017

Jesper Heldrup

10

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10 September 2017

Kristina Karrman

11

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10 September 2017

Bertil Johansson

12

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10 September 2017

Mats Heyman

13

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10 September 2017

Lars Palmqvist

15

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10 September 2017

8 October 2013

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10 September 2017

Pediatric Blood Cancer

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10 September 2017

61

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10 September 2017

424-430

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10 September 2017

3

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Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia

10 September 2017

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Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

21 January 2018

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Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL.

21 January 2018

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Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry.

21 January 2018

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Clinical and cytogenetic features of a population-based consecutive series of 285 pediatric T-cell acute lymphoblastic leukemias: rare T-cell receptor gene rearrangements are associated with poor outcome.

21 January 2018

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Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

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Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

21 January 2018

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Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

21 January 2018

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

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Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.

21 January 2018

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Impact of complex NOTCH1 mutations on survival in paediatric T-cell leukaemia.

21 January 2018

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NOTCH1 mutations in T-cell acute lymphoblastic leukemia: prognostic significance and implication in multifactorial leukemogenesis.

21 January 2018

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FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

21 January 2018

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The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.

21 January 2018

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FBXW7 mutation in adult T-cell and B-cell acute lymphocytic leukemias.

21 January 2018

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NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

21 January 2018

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NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951.

21 January 2018

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The indicative effect of Notch1 expression for the prognosis of T-cell acute lymphocytic leukemia: a systematic review

21 January 2018

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Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial.

21 January 2018

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Mutation nomenclature extensions and suggestions to describe complex mutations: a discussion

21 January 2018

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FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma

21 January 2018

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The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.

21 January 2018

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Prognostic significance of NOTCH1 and FBXW7 mutations in pediatric T-ALL

21 January 2018

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The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group

21 January 2018

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Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences.

21 January 2018

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Pediatric-inspired intensified therapy of adult T-ALL reveals the favorable outcome of NOTCH1/FBXW7 mutations, but not of low ERG/BAALC expression: a GRAALL study.

21 January 2018

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The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function

21 January 2018

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Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc

21 January 2018

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c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

21 January 2018

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Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and gamma-secretase inhibitors

21 January 2018

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Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells

21 January 2018

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Transcriptional elongation of c-myb is regulated by NF-kappaB (p50/RelB).

21 January 2018

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Transcriptional control of T-cell development

21 January 2018

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Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

21 January 2018

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Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/PBC.24803

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10 September 2017

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