ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch (Q39270542)

10 September 2017

ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch (English)

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10 September 2017

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7

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3 June 2020

Arjun Sengupta

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Aalim M Weljie

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3 June 2020

author name string

Steven Zhao

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AnnMarie Torres

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Ryan A Henry

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Sophie Trefely

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Martina Wallace

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Joyce V Lee

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Sydney L Campbell

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Yin-Ming Kuo

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Alexander J Frey

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Noah Meurs

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John M Viola

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Ian A Blair

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Christian M Metallo

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Nathaniel W Snyder

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Andrew J Andrews

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Kathryn E Wellen

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3 June 2020

publication date

1 October 2016

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10 September 2017

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3 June 2020

volume

17

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3 June 2020

page(s)

1037-1052

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3 June 2020

issue

4

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The metabolic fate of acetate in cancer

3 June 2020

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment

10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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An acetate switch regulates stress erythropoiesis

10 September 2017

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Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation

10 September 2017

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A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation

10 September 2017

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10 September 2017

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ATP citrate lyase knockdown impacts cancer stem cells in vitro

10 September 2017

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Lessons on conditional gene targeting in mouse adipose tissue

10 September 2017

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Histone acetylation regulates intracellular pH.

10 September 2017

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The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation

10 September 2017

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10 September 2017

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Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways

10 September 2017

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10 September 2017

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10 September 2017

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ATP-citrate lyase links cellular metabolism to histone acetylation

10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony

10 September 2017

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10 September 2017

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ATP citrate lyase is an important component of cell growth and transformation

10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms

10 September 2017

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10 September 2017

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Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function

14 September 2017

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14 September 2017

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14 September 2017

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Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism

14 September 2017

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The contribution of the large intestine to blood acetate in man.

25 September 2017

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Acetate is a bioenergetic substrate for human glioblastoma and brain metastases

25 September 2017

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17 June 2018

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Measurement of acetate in human blood by gas chromatography: effects of sample preparation, feeding, and various diseases

17 June 2018

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Quantitative analysis of acetyl-CoA production in hypoxic cancer cells reveals substantial contribution from acetate.

17 June 2018

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ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway.

21 August 2018

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Efficacy and safety of a novel dual modulator of adenosine triphosphate-citrate lyase and adenosine monophosphate-activated protein kinase in patients with hypercholesterolemia: results of a multicenter, randomized, double-blind, placebo-controlled,

21 August 2018

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Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation

21 August 2018

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Role of gastrointestinal tract and liver in acetate metabolism in rat and man

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27760311

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12 December 2020

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Identifiers

DOI

10.1016/J.CELREP.2016.09.069

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3 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27760311%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference