Control of gp130 expression by the mitogen-activated protein kinase ERK2. (Q39149971)

9 September 2017

Control of gp130 expression by the mitogen-activated protein kinase ERK2. (English)

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9 September 2017

N A Bonito

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9 September 2017

J Drechsler

2

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9 September 2017

S Stoecker

3

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9 September 2017

C R Carmo

4

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9 September 2017

M J Seckl

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9 September 2017

H M Hermanns

6

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9 September 2017

A P Costa-Pereira

7

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9 September 2017

language of work or name

English

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publication date

20 May 2013

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33

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17

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9 September 2017

2255-2263

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https://scigraph.springernature.com/pub.10.1038/onc.2013.159

9 September 2017

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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

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Inflammation and cancer: IL-6 and STAT3 complete the link.

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The STATs of cancer--new molecular targets come of age

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Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells

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Somatic STAT3 mutations in large granular lymphocytic leukemia

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Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

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Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.

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New and old functions of STAT3: a pivotal target for individualized treatment of cancer

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Malignant transformation but not normal cell growth depends on signal transducer and activator of transcription 3.

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

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STATs in cancer inflammation and immunity: a leading role for STAT3

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IL-6 signal transduction and its physiological roles: the signal orchestration model

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Acquiring signalling specificity from the cytokine receptor gp130.

21 January 2018

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Non-redundant signal transduction of interleukin-6-type cytokines. The adapter protein Shc is specifically recruited to rhe oncostatin M receptor

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Box 3-independent signaling mechanisms are involved in leukemia inhibitory factor receptor alpha- and gp130-mediated stimulation of mitogen-activated protein kinase. Evidence for participation of multiple signaling pathways which converge at Ras

21 January 2018

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Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

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Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells

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Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

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Signal transduction of inflammatory cytokines and tumor development

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Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor

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Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels

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An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

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Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

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p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.

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Working without kinase activity: phosphotransfer-independent functions of extracellular signal-regulated kinases

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Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation

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ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

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How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

21 January 2018

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21 January 2018

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ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

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Identification of novel RasGRF1 interacting partners by large-scale proteomic analysis

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ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events

21 January 2018

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ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis.

21 January 2018

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The N-terminal domain of ERK1 accounts for the functional differences with ERK2

21 January 2018

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Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling

21 January 2018

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DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation.

21 January 2018

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Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation

21 January 2018

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MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.159

Isolation and characterization of the human gp130 promoter. Regulation by STATS.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.159

Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)

21 January 2018

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Conditional gp130 deficient mouse mutants

21 January 2018

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Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation

21 January 2018

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p53 can inhibit cell proliferation through caspase-mediated cleavage of ERK2/MAPK.

21 January 2018

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Multiple kinases in the interferon-gamma response

21 January 2018

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A new mathematical model for relative quantification in real-time RT-PCR

21 January 2018

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Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.159

Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.159

Activated signal transduction kinases frequently occupy target genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.159

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.159

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Dimensions Publication ID

9 September 2017

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