Working without kinase activity: phosphotransfer-independent functions of extracellular signal-regulated kinases (Q37949574)

25 August 2017

Working without kinase activity: phosphotransfer-independent functions of extracellular signal-regulated kinases (English)

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25 August 2017

Javier Rodríguez

1

1 reference

PubMed ID

22028468

25 August 2017

Piero Crespo

series ordinal

2

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25 August 2017

25 October 2011

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25 August 2017

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25 August 2017

4

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25 August 2017

196

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25 August 2017

re3

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Differential regulation and properties of MAPKs

25 August 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Association of mitogen-activated protein kinase with the microtubule cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

ERK dimers and scaffold proteins: unexpected partners for a forgotten (cytoplasmic) task.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Live Cell Imaging of ERK and MEK: simple binding equilibrium explains the regulated nucleocytoplasmic distribution of ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Essential role of ERK dimers in the activation of cytoplasmic but not nuclear substrates by ERK-scaffold complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Scaffold proteins of MAP-kinase modules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Signalling ballet in space and time

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of actin-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

The mitogen-activated protein kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate binding and enzymatic specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

New insights into the catalytic activation of the MAPK phosphatase PAC-1 induced by its substrate MAPK ERK2 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Spatio-temporal regulation of mitogen-activated protein kinase (MAPK) signalling by protein phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Poly(ADP-ribose): novel functions for an old molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Type II topoisomerases--inhibitors, repair mechanisms and mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

DNA topoisomerase II enzymes as molecular targets for cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Chromatin-bound mitogen-activated protein kinases transmit dynamic signals in transcription complexes in beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

CCAAT/enhancer-binding protein-beta regulates interferon-induced transcription through a novel element

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

ERK implication in cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Role of A-type lamins in signaling, transcription, and chromatin organization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Lamins: 'structure goes cycling'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

IQGAP1 in cellular signaling: bridging the GAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Dystroglycan versatility in cell adhesion: a tale of multiple motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Paxillin and focal adhesion signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Identification and characterization of a general nuclear translocation signal in signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Stimulus-induced uncoupling of extracellular signal-regulated kinase phosphorylation from nuclear localization is dependent on docking domain interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Evidence for existence of a nuclear pore complex-mediated, cytosol-independent pathway of nuclear translocation of ERK MAP kinase in permeabilized cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

The nuclear localization of ERK2 occurs by mechanisms both independent of and dependent on energy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

Involvement of the activation loop of ERK in the detachment from cytosolic anchoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2002324

10.1126/SCISIGNAL.2002324

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

22028468