GarA is an essential regulator of metabolism in Mycobacterium tuberculosis (Q39107735)

9 September 2017

title

GarA is an essential regulator of metabolism in Mycobacterium tuberculosis (English)

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Mycobacterium tuberculosis

9 September 2017

main subject

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author

Marco Bellinzoni

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9 September 2017

8

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Francesca Boldrin

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Riccardo Manganelli

object named as

Riccardo Manganelli

9

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Helen M O'Hare

object named as

Helen M O'Hare

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Nathalie Barilone

6

object named as

Nathalie Barilone

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9 September 2017

4

Giulia Degiacomi

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9 September 2017

Marcello Ventura

1

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Barbara Rieck

2

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9 September 2017

Faisal Alzaidi

7

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9 September 2017

language of work or name

English

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publication date

8 September 2013

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9 September 2017

published in

Molecular Microbiology

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9 September 2017

volume

90

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9 September 2017

issue

2

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9 September 2017

page(s)

356-366

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Mycobacterium tuberculosis lipoamide dehydrogenase is encoded by Rv0462 and not by the lpdA or lpdB genes

9 September 2017

cites work

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Survival of mice infected with Mycobacterium smegmatis containing large DNA fragments from Mycobacterium tuberculosis

21 January 2018

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Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism

21 January 2018

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GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism

21 January 2018

1 reference

Development of a repressible mycobacterial promoter system based on two transcriptional repressors

21 January 2018

1 reference

Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation

21 January 2018

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Methionine sulfoximine resistance in Mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1.

21 January 2018

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The Mycobacterium tuberculosis protein serine/threonine kinase PknG is linked to cellular glutamate/glutamine levels and is important for growth in vivo

21 January 2018

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The FHA domain is a modular phosphopeptide recognition motif.

21 January 2018

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The FHA-containing protein GarA acts as a phosphorylation-dependent molecular switch in mycobacterial signaling

21 January 2018

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Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis

21 January 2018

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High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism

21 January 2018

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Control of glutamate homeostasis in Bacillus subtilis: a complex interplay between ammonium assimilation, glutamate biosynthesis and degradation.

21 January 2018

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An inhibitor of exported Mycobacterium tuberculosis glutamine synthetase selectively blocks the growth of pathogenic mycobacteria in axenic culture and in human monocytes: extracellular proteins as potential novel drug targets

21 January 2018

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Inhibition of Mycobacterium tuberculosis glutamine synthetase as a novel antibiotic strategy against tuberculosis: demonstration of efficacy in vivo

21 January 2018

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Genome wide analysis of the complete GlnR nitrogen-response regulon in Mycobacterium smegmatis

21 January 2018

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Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress

21 January 2018

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Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

21 January 2018

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The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages

21 January 2018

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Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection

21 January 2018

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Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence

21 January 2018

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Corynebacterial protein kinase G controls 2-oxoglutarate dehydrogenase activity via the phosphorylation status of the OdhI protein

21 January 2018

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An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis

21 January 2018

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Regulation of glutamate metabolism by protein kinases in mycobacteria

21 January 2018

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Use of a flexible cassette method to generate a double unmarked Mycobacterium tuberculosis tlyA plcABC mutant by gene replacement

21 January 2018

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Nitrogen metabolism in Streptomyces coelicolor: transcriptional and post-translational regulation

21 January 2018

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Genes required for mycobacterial growth defined by high density mutagenesis

21 January 2018

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Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes

21 January 2018

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Glutamine synthetase GlnA1 is essential for growth of Mycobacterium tuberculosis in human THP-1 macrophages and guinea pigs

21 January 2018

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Role of the methylcitrate cycle in propionate metabolism and detoxification in Mycobacterium smegmatis

21 January 2018

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Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions

21 January 2018

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Functional plasticity and allosteric regulation of α-ketoglutarate decarboxylase in central mycobacterial metabolism

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/MMI.12368

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9 September 2017

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