Modulation of intracellular calcium homeostasis blocks autophagosome formation (Q39106316)

9 September 2017

Modulation of intracellular calcium homeostasis blocks autophagosome formation (English)

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9 September 2017

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Anne Simonsen

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9 September 2017

10

Per O Seglen

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9 September 2017

Nikolai Engedal

1

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9 September 2017

Maria L Torgersen

2

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9 September 2017

Ingrid J Guldvik

3

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9 September 2017

Stefan J Barfeld

4

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9 September 2017

Daniela Bakula

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9 September 2017

Frank Sætre

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9 September 2017

Linda K Hagen

7

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9 September 2017

John B Patterson

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9 September 2017

Tassula Proikas-Cezanne

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9 September 2017

Ian G Mills

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9 September 2017

13 August 2013

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9 September 2017

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9 September 2017

9

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9 September 2017

10

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9 September 2017

1475-1490

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Autophagy in the Pathogenesis of Disease

9 September 2017

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Regulation of mammalian autophagy in physiology and pathophysiology.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Ca 2+ -dependent autophagy is enhanced by the pharmacological agent PK11195.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Withdrawal of essential amino acids increases autophagy by a pathway involving Ca2+/calmodulin-dependent kinase kinase-β (CaMKK-β)

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

AMPK-independent induction of autophagy by cytosolic Ca2+ increase.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling glucose regulatory protein 78 and AMPK.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Mechanisms of acute axonal degeneration in the optic nerve in vivo

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Autophagy is activated for cell survival after endoplasmic reticulum stress

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Mycobacterial lipoprotein activates autophagy via TLR2/1/CD14 and a functional vitamin D receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Pterostilbene, a natural small-molecular compound, promotes cytoprotective macroautophagy in vascular endothelial cells.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Guidelines for the use and interpretation of assays for monitoring autophagy

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Biological applications of ionophores

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Thapsigargin binds to and inhibits the cloned vanilloid receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Methods in mammalian autophagy research

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Assaying of autophagic protein degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Changes in the proteolytic activities of proteasomes and lysosomes in human fibroblasts produced by serum withdrawal, amino-acid deprivation and confluent conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Methods for monitoring autophagy from yeast to human

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Sequestration assays for mammalian autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Ca2+/calmodulin-dependent kinase (CaMK) signaling via CaMKI and AMP-activated protein kinase contributes to the regulation of WIPI-1 at the onset of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

T-cadherin attenuates the PERK branch of the unfolded protein response and protects vascular endothelial cells from endoplasmic reticulum stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Regulation of cell death: the calcium-apoptosis link

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

The crosstalk between autophagy and apoptosis: where does this lead?

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (P

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Molecular machinery of macroautophagy and its deregulation in diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Bone cell autophagy is regulated by environmental factors

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

A dual role for Ca(2+) in autophagy regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Activating transcription factor 4 and CCAAT/enhancer-binding protein-beta negatively regulate the mammalian target of rapamycin via Redd1 expression in response to oxidative and endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

SLC33A1/AT-1 protein regulates the induction of autophagy downstream of IRE1/XBP1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Autophagy and related mechanisms of lysosome-mediated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Autophagosomes form at ER-mitochondria contact sites

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Small molecule regulators of autophagy identified by an image-based high-throughput screen

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Lithium induces autophagy by inhibiting inositol monophosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

LC3 and GATE-16 N termini mediate membrane fusion processes required for autophagosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

SNARE proteins are required for macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Connections between SNAREs and autophagy

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.25900

Membrane fusion: grappling with SNARE and SM proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Autophagosome precursor maturation requires homotypic fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Role of SNAREs in membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25900

21 January 2018

Identifiers

DOI

10.4161/AUTO.25900

1 reference

9 September 2017

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