Challenges in assigning endocrine-specific modes of action: Recommendations for researchers and regulators (Q39099271)

9 September 2017

Challenges in assigning endocrine-specific modes of action: Recommendations for researchers and regulators (English)

1 reference

9 September 2017

Ellen M Mihaich

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Christoph Schäfers

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Lisa Ortego

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Yukio Kawashima

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Zhi-Chao Dang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Keith Solomon

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

publication date

15 December 2016

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Integrated Environmental Assessment and Management

9 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

13

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7 June 2020

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

280-292

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

Strategic selection of chemicals for testing. Part I. Functionalities and performance of basic selection methods.

7 June 2020

cites work

1 reference

Dynamic nature of alterations in the endocrine system of fathead minnows exposed to the fungicide prochloraz

21 January 2018

1 reference

Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment

21 January 2018

1 reference

Cross-species conservation of endocrine pathways: a critical analysis of tier 1 fish and rat screening assays with 12 model chemicals

21 January 2018

1 reference

Temporal changes in biological responses and uncertainty in assessing risks of endocrine-disrupting chemicals: insights from intensive time-course studies with fish

21 January 2018

1 reference

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

21 January 2018

1 reference

Comparison of the sensitivity of four native Canadian fish species to 17-α ethinylestradiol, using an in vitro liver explant assay

21 January 2018

1 reference

Assessment of the sensitivity of three North American fish species to disruptors of steroidogenesis using in vitro tissue explants

21 January 2018

1 reference

Hypothesis-driven weight of evidence framework for evaluating data within the US EPA's Endocrine Disruptor Screening Program

21 January 2018

1 reference

Relevance weighting of tier 1 endocrine screening endpoints by rank order

21 January 2018

1 reference

Ligula intestinalis infection is associated with alterations of both brain and gonad aromatase expression in roach (Rutilus rutilus).

21 January 2018

1 reference

Predicting modes of toxic action from chemical structure: an overview

21 January 2018

1 reference

Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model

21 January 2018

1 reference

Inhibition of vitellogenin gene induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is mediated by aryl hydrocarbon receptor 2 (AHR2) in zebrafish (Danio rerio).

21 January 2018

1 reference

Current limitations and recommendations to improve testing for the environmental assessment of endocrine active substances.

21 January 2018

1 reference

A weight of evidence assessment approach for adverse outcome pathways

21 January 2018

1 reference

Fish biomarkers for regulatory identification of endocrine disrupting chemicals.

21 January 2018

1 reference

Interpretation of fish biomarker data for identification, classification, risk assessment and testing of endocrine disrupting chemicals

21 January 2018

1 reference

Comparative endpoint sensitivity of in vitro estrogen agonist assays.

21 January 2018

1 reference

Interpreting stress responses during routine toxicity studies: a review of the biology, impact, and assessment.

21 January 2018

1 reference

One-way inhibiting cross-talk between arylhydrocarbon receptor (AhR) and estrogen receptor (ER) signaling in primary cultures of rainbow trout hepatocytes

21 January 2018

1 reference

Morphologic effects of the stress response in fish

21 January 2018

1 reference

Parasitism in fish--an endocrine modulator of ecological relevance?

21 January 2018

1 reference

CYP2D6 and tamoxifen: DNA matters in breast cancer

21 January 2018

1 reference

Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor.

21 January 2018

1 reference

Agrichemicals chronically inhibit the cortisol response to stress in fish.

21 January 2018

1 reference

Leveraging existing data for prioritization of the ecological risks of human and veterinary pharmaceuticals to aquatic organisms

21 January 2018

1 reference

Molecular target sequence similarity as a basis for species extrapolation to assess the ecological risk of chemicals with known modes of action

21 January 2018

1 reference

Editor's Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity.

21 January 2018

1 reference

Stressors, glucocorticoids and ovarian function in teleosts

21 January 2018

1 reference

Aqueous exposure to 4-nonylphenol and 17beta-estradiol increases stress sensitivity and disrupts ion regulatory ability of juvenile Atlantic salmon.

21 January 2018

1 reference

Biochemical and physiological responses in liver and muscle of rainbow trout after long-term exposure to propiconazole.

21 January 2018

1 reference

Effects of exposure to sublethal propiconazole on the antioxidant defense system and Na+-K+-ATPase activity in brain of rainbow trout, Oncorhynchus mykiss

21 January 2018

1 reference

Multiple biomarkers responses in juvenile rainbow trout, Oncorhynchus mykiss, after acute exposure to a fungicide propiconazole.

21 January 2018

1 reference

Systematic comparison of study quality criteria

21 January 2018

1 reference

Endocrine disruption: historical perspectives and its impact on the future of toxicology testing

21 January 2018

1 reference

21 January 2018

1 reference

Information Quality in Regulatory Decision Making: Peer Review versus Good Laboratory Practice

21 January 2018

1 reference

New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis.

21 January 2018

1 reference

Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence

21 January 2018

1 reference

Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances.

21 January 2018

1 reference

Uncertainties in biological responses that influence hazard and risk approaches to the regulation of endocrine active substances.

21 January 2018

1 reference

Determinants of variability in acute to chronic toxicity ratios for aquatic invertebrates and fish.

21 January 2018

1 reference

Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays

21 January 2018

1 reference

Propiconazole inhibits steroidogenesis and reproduction in the fathead minnow (Pimephales promelas).

21 January 2018

1 reference

Inhibition of gametogenesis by the cestode Ligula intestinalis in roach (Rutilus rutilus) is attenuated under laboratory conditions.

21 January 2018

1 reference

Use of acute and chronic ecotoxicity data in environmental risk assessment of pharmaceuticals

21 January 2018

1 reference

Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor

21 January 2018

1 reference

What is normal? A characterization of the values and variability in reproductive endpoints of the fathead minnow, Pimephales promelas.

21 January 2018

1 reference

Weight of evidence: a review of concept and methods

21 January 2018

1 reference

Test concentration setting for fish in vivo endocrine screening assays

21 January 2018

1 reference

Are all chemicals endocrine disruptors?

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IEAM.1883

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27976826%20AND%20SRC:MED&resulttype=core&format=json

release_bctbagmkabfzxba27a5kgsem7y

7 June 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/bctbagmkabfzxba27a5kgsem7y

mapped directly with Wikidata item

24 November 2022

based on heuristic

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