Identification of 6-demethoxy-6-methylgeldanamycin and its implication of geldanamycin biosynthesis (Q39084395)

8 September 2017

Identification of 6-demethoxy-6-methylgeldanamycin and its implication of geldanamycin biosynthesis (English)

1 reference

8 September 2017

Siyang Ni

1

1 reference

8 September 2017

Bingya Jiang

2

1 reference

8 September 2017

Linzhuan Wu

3

1 reference

8 September 2017

Yiguang Wang

4

1 reference

8 September 2017

Hongxia Zhou

5

1 reference

8 September 2017

Weiqing He

6

1 reference

8 September 2017

Hongyuan Wang

7

1 reference

8 September 2017

Jianhua Zhu

8

1 reference

8 September 2017

Shufen Li

9

1 reference

8 September 2017

Ting Li

10

1 reference

8 September 2017

Kan Zhang

11

1 reference

8 September 2017

language of work or name

1 reference

9 October 2013

1 reference

The Journal of Antibiotics

8 September 2017

1 reference

8 September 2017

67

1 reference

8 September 2017

2

1 reference

8 September 2017

183-185

1 reference

https://scigraph.springernature.com/pub.10.1038/ja.2013.94

8 September 2017

0 references

cites work

Geldanamycin and its anti-cancer activities

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

A phase II study of 17-allylamino-17-demethoxygeldanamycin in metastatic or locally advanced, unresectable breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

New, highly active nonbenzoquinone geldanamycin derivatives by using mutasynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Broad substrate specificity of the amide synthase in S. hygroscopicus--new 20-membered macrolactones derived from geldanamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Enzymatic glycosylation of nonbenzoquinone geldanamycin analogs via Bacillus UDP-glycosyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Methanethiol as a catabolite of methionine provides methylthio- group for chemical formation of 19-S-methylgeldanamycin and 17,19-dimethylthioherbimycin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

7-O-descarbamoyl-7-hydroxygeldanamycin, a minor component from the gdmN disruption mutant of Streptomyces hygroscopicus 17997.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Inactivation of the carbamoyltransferase gene refines post-polyketide synthase modification steps in the biosynthesis of the antitumor agent geldanamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

A tylosin ketoreductase reveals how chirality is determined in polyketides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Prediction and manipulation of the stereochemistry of enoylreduction in modular polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

The methoxymalonyl-acyl carrier protein biosynthesis locus and the nearby gene with the beta-ketoacyl synthase domain are involved in the biosynthesis of galbonolides in Streptomyces galbus, but these loci are separate from the modular polyketide sy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Isolation and structure of homotemsirolimuses A, B, and C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Engineered biosynthesis of geldanamycin analogs for Hsp90 inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

New Geldanamycin Analogs from Streptomyces hygroscopicus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

Geldanamycin, a new antibiotic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

7 January 2021

Novel 4,5-dihydro-thiazinogeldanamycin in a gdmP mutant strain of Streptomyces hygroscopicus 17997

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

7 January 2021

A pair of sulfur-containing geldanamycin analogs, 19-S-methylgeldanamycin and 4,5-dihydro- 19-S-methylgeldanamycin, from Streptomyces hygroscopicus 17997

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

7 January 2021

Identification of 4,5-Dihydro-4-hydroxygeldanamycins As Shunt Products of Geldanamycin Biosynthesis

1 reference

https://api.crossref.org/works/10.1038%2FJA.2013.94

7 January 2021

Identifiers

DOI

10.1038/JA.2013.94

1 reference

8 September 2017

1 reference