Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures (Q39059671)

8 September 2017

Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures (English)

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8 September 2017

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author name string

Savvas N Savvides

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2

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8 September 2017

28 December 2016

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Nature Reviews Immunology

8 September 2017

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8 September 2017

17

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8 September 2017

112-129

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8 September 2017

2

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https://scigraph.springernature.com/pub.10.1038/nri.2016.134

8 September 2017

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21 January 2018

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https://api.crossref.org/works/10.1038%2FNRI.2016.134

Fc-fusion proteins: new developments and future perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Fc fusion as a platform technology: potential for modulating immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Cytokine traps: multi-component, high-affinity blockers of cytokine action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

VEGF-Trap: a VEGF blocker with potent antitumor effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Adenovirus-mediated overexpression of soluble ST2 provides a protective effect on lipopolysaccharide-induced acute lung injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

A single amino acid determines the immunostimulatory activity of interleukin 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Pathogen-derived immunomodulatory molecules: future immunotherapeutics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Gene transfer of virally encoded chemokine antagonists vMIP-II and MC148 prolongs cardiac allograft survival and inhibits donor-specific immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

The viral anti-inflammatory chemokine-binding protein M-T7 reduces intimal hyperplasia after vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Inhibition of intimal hyperplasia in transgenic mice conditionally expressing the chemokine-binding protein M3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Attenuation of TNF-driven murine ileitis by intestinal expression of the viral immunomodulator CrmD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Virus-derived anti-inflammatory proteins: potential therapeutics for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Transplant vasculopathy: viral anti-inflammatory serpin regulation of atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Inhibition of chemokine-glycosaminoglycan interactions in donor tissue reduces mouse allograft vasculopathy and transplant rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Insights into cytokine-receptor interactions from cytokine engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Non-immunoglobulin scaffolds: a focus on their targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Structural basis of IL-23 antagonism by an Alphabody protein scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Structural and biophysical studies of the human IL-7/IL-7Ralpha complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Structural determinants of growth factor binding and specificity by VEGF receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Structural insights into the interaction of IL-33 with its receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Orf virus interleukin-10 inhibits cytokine synthesis in activated human THP-1 monocytes, but only partially impairs their proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Sequence and functional analysis of a homolog of interleukin-10 encoded by the parapoxvirus orf virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Structure of an extracellular gp130 cytokine receptor signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Glycoprotein G isoforms from some alphaherpesviruses function as broad-spectrum chemokine binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FNRI.2016.134

31 March 2020

12 December 2020

An essential role for ectodomain shedding in mammalian development

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Selective recognition of the membrane-bound CX3C chemokine, fractalkine, by the human cytomegalovirus-encoded broad-spectrum receptor US28

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

The gammaherpesvirus chemokine binding protein can inhibit the interaction of chemokines with glycosaminoglycans.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Local blockade of allergic airway hyperreactivity and inflammation by the poxvirus-derived pan-CC-chemokine inhibitor vCCI

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRI.2016.134

Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130

31 March 2020

1 reference

12 December 2020

The Epstein-Barr virus BARF1 gene encodes a novel, soluble colony-stimulating factor-1 receptor.

1 reference

12 December 2020

The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1

1 reference

12 December 2020

A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor

1 reference

12 December 2020

β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6

1 reference

12 December 2020

Vaccinia, cowpox, and camelpox viruses encode soluble gamma interferon receptors with novel broad species specificity

1 reference

12 December 2020

Binding of IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble IL-1 receptors in synovial fluids.

1 reference

12 December 2020

Soluble cytokine receptors

1 reference

12 December 2020

Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses.

1 reference

12 December 2020

The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI.2016.134

1 reference

PubMed ID

28028310

Dimensions Publication ID

8 September 2017

0 references

1 reference

PubMed ID

28028310