LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade (Q39043614)

8 September 2017

LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade (English)

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8 September 2017

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Y Hasegawa

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8 September 2017

I Tanaka

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H Osada

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M Fujii

3

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8 September 2017

A Fukatsu

4

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T Hida

5

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Y Horio

6

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Y Kondo

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A Sato

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T Tsujimura

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8 September 2017

Y Sekido

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8 September 2017

language of work or name

English

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publication date

16 December 2013

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8 September 2017

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34

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73-83

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https://scigraph.springernature.com/pub.10.1038/onc.2013.528

8 September 2017

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cites work

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Malignant mesothelioma: facts, myths, and hypotheses

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Advances in malignant mesothelioma

21 January 2018

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Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma

21 January 2018

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The pathogenesis of mesothelioma

21 January 2018

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Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.528

High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.528

Elucidation of a universal size-control mechanism in Drosophila and mammals

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.528

Filling out the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.528

Herding Hippos: regulating growth in flies and man.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.528

TEAD mediates YAP-dependent gene induction and growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

YAP1 is involved in mesothelioma development and negatively regulated by Merlin through phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

LATS2 is a tumor suppressor gene of malignant mesothelioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Scaffold proteins confer diverse regulatory properties to protein kinase cascades.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Scaffold proteins and immune-cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Signal transduction: hanging on a scaffold.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Ajuba LIM proteins are negative regulators of the Hippo signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

The Drosophila RASSF homolog antagonizes the hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Mechanisms of trophectoderm fate specification in preimplantation mouse development.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.528

Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Ajuba: a new microtubule-associated protein that interacts with BUBR1 and Aurora B at kinetochores in metaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Growth control by committee: intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Hippo pathway regulation by cell morphology and stress fibers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Modulating F-actin organization induces organ growth by affecting the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

Malignant pleural mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

31 March 2020

Malignant mesothelioma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.528

FoxM1: at the crossroads of ageing and cancer

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24336325

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24336325

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2013.528

1 reference

8 September 2017

1 reference