YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes. (Q39404727)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22286761%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes (English)

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21 January 2020

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8

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21 January 2020

author name string

T Mizuno

1

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21 January 2020

H Murakami

2

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21 January 2020

M Fujii

3

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21 January 2020

F Ishiguro

4

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21 January 2020

I Tanaka

5

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21 January 2020

Y Kondo

6

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21 January 2020

S Akatsuka

7

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21 January 2020

K Yokoi

9

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21 January 2020

H Osada

10

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21 January 2020

Y Sekido

11

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21 January 2020

language of work or name

English

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publication date

30 January 2012

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21 January 2020

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21 January 2020

volume

31

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21 January 2020

page(s)

5117-5122

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21 January 2020

issue

49

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describes a project that uses

21 January 2020

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https://scigraph.springernature.com/pub.10.1038/onc.2012.5

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cites work

Mesothelioma epidemiology, carcinogenesis, and pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Advances in malignant mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The pathogenesis of mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Germline BAP1 mutations predispose to malignant mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Elucidation of a universal size-control mechanism in Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Filling out the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

LATS2 is a tumor suppressor gene of malignant mesothelioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

YAP1 is involved in mesothelioma development and negatively regulated by Merlin through phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

YAP regulates neural progenitor cell number via the TEA domain transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

TEAD mediates YAP-dependent gene induction and growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Hippo pathway effector Yap is an ovarian cancer oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

YAP is a candidate oncogene for esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

Malignant pleural mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5

The use of CDKN2A deletion as a diagnostic marker for malignant mesothelioma in body cavity effusions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.5