Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation (Q39041714)

8 September 2017

Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation (English)

1 reference

8 September 2017

13

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12 June 2020

Zhongwei Zhou

4

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12 June 2020

Cornelis F Calkhoven

11

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12 June 2020

author name string

WooKee Min

1

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12 June 2020

Christopher Bruhn

2

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12 June 2020

Paulius Grigaravicius

3

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12 June 2020

Fu Li

5

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12 June 2020

Anja Krüger

6

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12 June 2020

Bénazir Siddeek

7

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12 June 2020

Karl-Otto Greulich

8

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12 June 2020

Oliver Popp

9

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12 June 2020

Chris Meisezahl

10

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12 June 2020

Alexander Bürkle

12

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12 June 2020

Zhao-Qi Wang

14

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12 June 2020

language of work or name

English

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publication date

1 January 2013

1 reference

8 September 2017

Nature Communications

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12 June 2020

volume

4

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12 June 2020

page(s)

2993

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https://scigraph.springernature.com/pub.10.1038/ncomms3993

12 June 2020

exact match

0 references

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Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

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Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase

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Chk1 promotes replication fork progression by controlling replication initiation

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Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential

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Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

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Single-strand break repair and genetic disease

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Poly(ADP-ribose): novel functions for an old molecule

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The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets

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Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents

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Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition

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ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity.

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Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

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Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

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Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

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APLF (C2orf13) is a novel component of poly(ADP-ribose) signaling in mammalian cells.

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7 January 2021

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

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Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

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7 January 2021

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

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Learning how to read ADP-ribosylation

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Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

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Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

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Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice

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Inhibition of DNA synthesis by ionizing radiation: a marker for an S-phase checkpoint

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Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis

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Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

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Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

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Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage

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A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1.

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Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.

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Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

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7 January 2021

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Anticancer therapy with checkpoint inhibitors: what, where and when?

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7 January 2021

PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA.

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7 January 2021

PARP is important for genomic stability but dispensable in apoptosis

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7 January 2021

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

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7 January 2021

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway

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7 January 2021

High resolution fractionation and characterization of ADP-ribose polymers

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7 January 2021

Poly(ADP-ribose) quantification at the femtomole level in mammalian cells

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7 January 2021

Characterization of polymers of adenosine diphosphate ribose generated in vitro and in vivo

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7 January 2021

Chk2 activation and phosphorylation-dependent oligomerization

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7 January 2021

Identifiers

DOI

10.1038/NCOMMS3993

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24356582%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 June 2020

ADS bibcode

2013NatCo...4.2993M

0 references

1014680261

0 references

Fatcat ID

release_w2rhor644jabrfhqxvskz5e2ka

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/w2rhor644jabrfhqxvskz5e2ka

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24356582%20AND%20SRC:MED&resulttype=core&format=json