Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints (Q24538300)

6 July 2017

title

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints (English)

1 reference

6 July 2017

Hui Zhao

1

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6 July 2017

Janis L Watkins

series ordinal

2

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6 July 2017

Helen Piwnica-Worms

series ordinal

3

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6 July 2017

publication date

24 October 2002

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Proceedings of the National Academy of Sciences of the United States of America

6 July 2017

language of work or name

English

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published in

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6 July 2017

volume

99

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6 July 2017

issue

23

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6 July 2017

page(s)

14795-14800

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

6 July 2017

cites work

1 reference

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24 March 2017

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Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

24 March 2017

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ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

24 March 2017

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Overproduction of human Myt1 kinase induces a G2 cell cycle delay by interfering with the intracellular trafficking of Cdc2-cyclin B1 complexes

24 March 2017

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A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

24 March 2017

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S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

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Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice

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The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1

24 March 2017

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The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

24 March 2017

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An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage

24 March 2017

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A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2

24 March 2017

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C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding

24 March 2017

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Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

24 March 2017

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Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

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Roles of active site residues and the NH2-terminal domain in the catalysis and substrate binding of human Cdc25

24 March 2017

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Rapid destruction of human Cdc25A in response to DNA damage

24 March 2017

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Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases

24 March 2017

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Cdc25A is a novel phosphatase functioning early in the cell cycle

24 March 2017

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Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

24 March 2017

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Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

27 September 2017

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Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

27 September 2017

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Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

27 September 2017

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DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding

27 September 2017

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Replication Checkpoint Enforced by Kinases Cds1 and Chk1

27 September 2017

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14-3-3 Proteins Act as Negative Regulators of the Mitotic Inducer Cdc25 inXenopusEgg Extracts

27 September 2017

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p56(chk1) protein kinase is required for the DNA replication checkpoint at 37 degrees C in fission yeast

27 September 2017

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Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

27 September 2017

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Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast

27 September 2017

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Purification of a serine kinase that associates with and phosphorylates human Cdc25C on serine 216.

27 September 2017

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Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

27 September 2017

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rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint

27 September 2017

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https://api.crossref.org/works/10.1073%2FPNAS.182557299

Mechanisms of p34cdc2 regulation

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.182557299

Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.182557299

Cdc25A stability is controlled by the ubiquitin-proteasome pathway during cell cycle progression and terminal differentiation.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.182557299

Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.182557299

21 January 2018

Identifiers

DOI

10.1073/PNAS.182557299

1 reference

OpenCitations bibliographic resource ID

6 July 2017

0 references

1074243

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

6 July 2017

1 reference