Mechanisms of RIPK3-induced inflammation (Q39038663)

8 September 2017

Mechanisms of RIPK3-induced inflammation (English)

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8 September 2017

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Motti Gerlic

3

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author name string

Inbar Shlomovitz

series ordinal

1

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PubMed ID

27974745

8 September 2017

Sefi Zargrian

series ordinal

2

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8 September 2017

15 December 2016

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Immunology & Cell Biology

8 September 2017

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8 September 2017

95

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8 September 2017

2

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8 September 2017

166-172

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https://scigraph.springernature.com/pub.10.1038/icb.2016.124

8 September 2017

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cites work

RIP3, a novel apoptosis-inducing kinase

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Mouse receptor interacting protein 3 does not contain a caspase-recruiting or a death domain but induces apoptosis and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

The diverse role of RIP kinases in necroptosis and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

A novel function of RIP1 in postnatal development and immune homeostasis by protecting against RIP3-dependent necroptosis and FADD-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Necroptosis and its role in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIP3 induces apoptosis independent of pronecrotic kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Pyroptotic death storms and cytopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIPK3-dependent cell death and inflammasome activation in FLT3-ITD expressing LICs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Human Monocytes Engage an Alternative Inflammasome Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

A20 restricts ubiquitination of pro-interleukin-1β protein complexes and suppresses NLRP3 inflammasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Manipulation of apoptosis and necroptosis signaling by herpesviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

IAP gene deletion and conditional knockout models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Structural determinants of caspase-9 inhibition by the vaccinia virus protein, F1L

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Suppression of RIP3-dependent necroptosis by human cytomegalovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIP1/RIP3 binding to HSV-1 ICP6 initiates necroptosis to restrict virus propagation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Herpes simplex virus suppresses necroptosis in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Toxin-induced necroptosis is a major mechanism of Staphylococcus aureus lung damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Activation of necroptosis in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

A role of RIP3-mediated macrophage necrosis in atherosclerosis development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Programmed necrosis, not apoptosis, is a key mediator of cell loss and DAMP-mediated inflammation in dsRNA-induced retinal degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Protective roles for caspase-8 and cFLIP in adult homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Microglia and necroptosis: The culprits of neuronal cell death in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Upregulated RIP3 Expression Potentiates MLKL Phosphorylation-Mediated Programmed Necrosis in Toxic Epidermal Necrolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIPK3-Mediated Necroptosis and Apoptosis Contributes to Renal Tubular Cell Progressive Loss and Chronic Kidney Disease Progression in Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Serum levels of RIPK3 and troponin I as potential biomarkers for predicting impaired left ventricular function in patients with myocardial infarction with ST segment elevation and normal troponin I levels prior percutaneous coronary intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

inferred from DOI database lookup

7 January 2021

based on heuristic

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2016.124

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ICB.2016.124

1 reference

PubMed ID

27974745

Dimensions Publication ID

8 September 2017

0 references

1 reference

PubMed ID

27974745