Protective roles for caspase-8 and cFLIP in adult homeostasis. (Q37349786)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24095739%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Protective roles for caspase-8 and cFLIP in adult homeostasis (English)

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26 February 2020

1

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26 February 2020

Prajwal Gurung

8

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Thirumala-Devi Kanneganti

26 February 2020

10

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26 February 2020

Douglas R. Green

11

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26 February 2020

author name string

Andrew Oberst

2

1 reference

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26 February 2020

Christopher P Dillon

3

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26 February 2020

Laura J Janke

4

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26 February 2020

Sandra Milasta

5

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26 February 2020

Diego A Rodriguez

7

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26 February 2020

Chandra Savage

9

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26 February 2020

John R Lukens

6

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26 February 2020

language of work or name

English

0 references

publication date

3 October 2013

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26 February 2020

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26 February 2020

volume

5

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26 February 2020

issue

2

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26 February 2020

page(s)

340-348

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c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis

26 February 2020

cites work

1 reference

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TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation.

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Survival function of the FADD-CASPASE-8-cFLIP(L) complex

6 September 2017

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6 September 2017

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6 September 2017

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Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

6 September 2017

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

6 September 2017

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

6 September 2017

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RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

6 September 2017

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Dynamic expression of epidermal caspase 8 simulates a wound healing response

6 September 2017

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Caspase inhibitors: viral, cellular and chemical

6 September 2017

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The protein structures that shape caspase activity, specificity, activation and inhibition

6 September 2017

1 reference

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Caspase-8 serves both apoptotic and nonapoptotic roles

6 September 2017

1 reference

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Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

6 September 2017

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Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

6 September 2017

1 reference

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An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes.

6 September 2017

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FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

6 September 2017

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Inhibition of death receptor signals by cellular FLIP

6 September 2017

1 reference

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RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein

6 September 2017

1 reference

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Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

14 September 2017

1 reference

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Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

28 September 2017

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

26 June 2018

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Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver

26 June 2018

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Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.

26 June 2018

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Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

2 September 2018

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RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

2 September 2018

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2 September 2018

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Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C.

2 September 2018

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2 September 2018

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Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression.

2 September 2018

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The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24095739

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24095739

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Anti-inflammatory functions of the "apoptotic" caspases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24095739

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2013.08.045

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24095739%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24095739%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

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