The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans (Q39004698)

8 September 2017

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title

The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans (English)

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G protein-coupled receptor

8 September 2017

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author name string

Peter Kovacs

series ordinal

1

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PubMed ID

27832489

8 September 2017

Torsten Schöneberg

series ordinal

2

1 reference

8 September 2017

1 January 2016

1 reference

Handbook of experimental pharmacology

8 September 2017

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8 September 2017

234

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8 September 2017

179-217

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A global reference for human genetic variation

8 September 2017

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Genome 10K: a proposal to obtain whole-genome sequence for 10,000 vertebrate species

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The Genome 10K Project: a way forward

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Whole-genome analyses resolve early branches in the tree of life of modern birds

21 January 2018

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Toward a new history and geography of human genes informed by ancient DNA

21 January 2018

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Kiwi genome provides insights into evolution of a nocturnal lifestyle

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The evolution of the GPCR signaling system in eukaryotes: modularity, conservation, and the transition to metazoan multicellularity

21 January 2018

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The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi

21 January 2018

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The role of G protein-coupled receptors in the early evolution of neurotransmission and the nervous system

21 January 2018

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The Secretin GPCRs descended from the family of Adhesion GPCRs.

21 January 2018

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Inactivation of the EGF-TM7 receptor EMR4 after the Pan-Homo divergence.

21 January 2018

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Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse.

21 January 2018

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Population Genomics of Human Adaptation

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Genetic signatures of strong recent positive selection at the lactase gene

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Detecting natural selection in genomic data

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Recent human adaptation: genomic approaches, interpretation and insights

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PAML 4: phylogenetic analysis by maximum likelihood

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Adaptive protein evolution at the Adh locus in Drosophila

21 January 2018

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Interrogating a high-density SNP map for signatures of natural selection

21 January 2018

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Positive natural selection in the human lineage

21 January 2018

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Detecting recent positive selection in the human genome from haplotype structure

21 January 2018

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A map of recent positive selection in the human genome

21 January 2018

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A new approach for using genome scans to detect recent positive selection in the human genome

21 January 2018

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Genome-wide detection and characterization of positive selection in human populations

21 January 2018

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Genome-wide signatures of convergent evolution in echolocating mammals

21 January 2018

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Natural selection on protein-coding genes in the human genome

21 January 2018

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Uncovering adaptive evolution in the human lineage.

21 January 2018

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Patterns of positive selection in six Mammalian genomes

21 January 2018

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More genes underwent positive selection in chimpanzee evolution than in human evolution

21 January 2018

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Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques

21 January 2018

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Multiplex amplification of ancient DNA.

21 January 2018

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Sequencing the nuclear genome of the extinct woolly mammoth

21 January 2018

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Ancient biomolecules from deep ice cores reveal a forested southern Greenland

21 January 2018

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A melanocortin 1 receptor allele suggests varying pigmentation among Neanderthals

21 January 2018

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Nuclear gene indicates coat-color polymorphism in mammoths

21 January 2018

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A Draft Sequence of the Neandertal Genome

21 January 2018

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The complete genome sequence of a Neanderthal from the Altai Mountains

21 January 2018

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Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans

21 January 2018

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Patterns of coding variation in the complete exomes of three Neandertals.

21 January 2018

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A high-coverage genome sequence from an archaic Denisovan individual

21 January 2018

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Targeted investigation of the Neandertal genome by array-based sequence capture

21 January 2018

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Genomic analysis of natural selection and phenotypic variation in high-altitude Mongolians

21 January 2018

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Global diversity, population stratification, and selection of human copy-number variation

21 January 2018

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Identifying selected regions from heterozygosity and divergence using a light-coverage genomic dataset from two human populations

21 January 2018

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Genome-wide analysis of cold adaptation in indigenous Siberian populations

21 January 2018

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A practical genome scan for population-specific strong selective sweeps that have reached fixation

21 January 2018

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Signals of recent positive selection in a worldwide sample of human populations

21 January 2018

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A map of human genome variation from population-scale sequencing

21 January 2018

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Fine-scale detection of population-specific linkage disequilibrium using haplotype entropy in the human genome

21 January 2018

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A second generation human haplotype map of over 3.1 million SNPs

21 January 2018

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Genetic signatures reveal high-altitude adaptation in a set of ethiopian populations

21 January 2018

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Targets of balancing selection in the human genome

21 January 2018

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Genetic variation and recent positive selection in worldwide human populations: evidence from nearly 1 million SNPs

21 January 2018

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Pseudogenes: Are They “Junk” or Functional DNA?

21 January 2018

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Major taste loss in carnivorous mammals.

21 January 2018

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The rise and fall of the chemoattractant receptor GPR33

21 January 2018

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

21 January 2018

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The genetic and evolutionary basis of colour variation in vertebrates

21 January 2018

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Inactivation of the F4/80 glycoprotein in the mouse germ line

21 January 2018

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Identification of the cystic fibrosis gene: genetic analysis

21 January 2018

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The Huntington's disease candidate region exhibits many different haplotypes

21 January 2018

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Mapping complex disease loci in whole-genome association studies

21 January 2018

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

21 January 2018

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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

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A genome-wide scan for urinary albumin excretion in hypertensive families

21 January 2018

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Gene expression profiling of human lung tissue from smokers with severe emphysema.

21 January 2018

1 reference

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A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2.

21 January 2018

1 reference

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A genome-wide scan of serum lipid levels in the Old Order Amish

21 January 2018

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A genome wide linkage search for breast cancer susceptibility genes

21 January 2018

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A genome screen of families with multiple cases of prostate cancer: evidence of genetic heterogeneity

21 January 2018

1 reference

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Genome-wide scan for linkage in finnish hereditary prostate cancer (HPC) families identifies novel susceptibility loci at 11q14 and 3p25-26.

21 January 2018

1 reference

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A whole genome screen for linkage in Turkish multiple sclerosis

21 January 2018

1 reference

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Quantitative trait linkage analysis of lipid-related traits in familial type 2 diabetes: evidence for linkage of triglyceride levels to chromosome 19q.

21 January 2018

1 reference

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Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia

21 January 2018

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A quantitative trait locus (QTL) on chromosome 6q influences birth weight in two independent family studies.

21 January 2018

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Genome‐wide scan of Swedish families with hereditary prostate cancer: Suggestive evidence of linkage at 5q11.2 and 19p13.3

21 January 2018

1 reference

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Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24.

21 January 2018

1 reference

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Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease

21 January 2018

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Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure

21 January 2018

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Quantitative trait loci for apolipoprotein B, cholesterol, and triglycerides in familial combined hyperlipidemia pedigrees

21 January 2018

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Linkage analysis of chromosome 1 with essential hypertension and blood pressure quantitative traits in Chinese families.

21 January 2018

1 reference

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Stratification analysis of an osteoarthritis genome screen-suggestive linkage to chromosomes 4, 6, and 16.

21 January 2018

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Two major QTLs and several others relate to factors of metabolic syndrome in the family blood pressure program

21 January 2018

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A follow-up linkage study for quantitative trait loci contributing to obesity-related phenotypes.

21 January 2018

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Genome-wide linkage analysis of systolic and diastolic blood pressure: the Québec Family Study

21 January 2018

1 reference

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Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes.

21 January 2018

1 reference

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Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24.

21 January 2018

1 reference

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Genome scan for human obesity and linkage to markers in 20q13.

21 January 2018

1 reference

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A genomic scan of families with prostate cancer identifies multiple regions of interest

21 January 2018

1 reference

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Genomic scan of 254 hereditary prostate cancer families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genomic scan of glucose and insulin metabolism phenotypes: the HERITAGE Family Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Linkage of high-density lipoprotein-cholesterol concentrations to a locus on chromosome 9p in Mexican Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort.

21 January 2018

1 reference

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Linkage analysis of circulating levels of adiponectin in Hispanic children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Evidence of a novel quantitative-trait locus for obesity on chromosome 4p in Mexican Americans

21 January 2018

1 reference

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A major predisposition locus for severe obesity, at 4p15-p14

21 January 2018

1 reference

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Confirmation of linkage of prostate cancer aggressiveness with chromosome 19q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide scan of predisposing loci for increased diastolic blood pressure in Finnish siblings

21 January 2018

1 reference

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Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics

21 January 2018

1 reference

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Genomic search for prostate cancer predisposition loci in Utah pedigrees

21 January 2018

1 reference

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Refinement of the 22q12-q13 breast cancer--associated region: evidence of TMPRSS6 as a candidate gene in an eastern Finnish population

21 January 2018

1 reference

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A genome-wide scan for body mass index among Nigerian families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Evidence of QTLs on chromosomes 1q42 and 8q24 for LDL-cholesterol and apoB levels in the HERITAGE family study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome‐wide scan for prostate cancer susceptibility genes in the Johns Hopkins hereditary prostate cancer families

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Linkage of prostate cancer susceptibility loci to chromosome 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide scan for obesity in African-Americans

21 January 2018

1 reference

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Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study

21 January 2018

1 reference

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Linkage of asthma to markers on chromosome 12 in a sample of 240 families using quantitative phenotype scores.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide linkage analysis reveals evidence of multiple regions that influence variation in plasma lipid and apolipoprotein levels associated with risk of coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Evidence of QTLs on chromosomes 13q and 14q for triglycerides before and after 20 weeks of exercise training: the HERITAGE Family Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide scan for adiposity-related phenotypes in adults from American Samoa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome screen of multiplex sibships with prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic whites and blacks: the HERITAGE Family Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome scan for predisposing loci for distal interphalangeal joint osteoarthritis: evidence for a locus on 2q.

21 January 2018

1 reference

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A second-generation genomic screen for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Quantitative trait loci on chromosome 8q24 for pancreatic beta-cell function and 7q11 for insulin sensitivity in obese nondiabetic white and black families: evidence from genome-wide linkage scans in the NHLBI Hypertension Genetic Epidemiology Netwo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genomewide scan for prostate cancer-aggressiveness loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide search for susceptibility genes to type 2 diabetes in West Africans: potential role of C-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Evidence for a gene influencing fasting LDL cholesterol and triglyceride levels on chromosome 21q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A cholesterol-lowering gene maps to chromosome 13q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Interaction between obesity-susceptibility loci in chromosome regions 2p25-p24 and 13q13-q21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Fasting insulin and obesity-related phenotypes are linked to chromosome 2p: the Strong Heart Family Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

The quantitative trait locus on chromosome 2 for serum leptin levels is confirmed in African-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Linkage and association studies between the proopiomelanocortin (POMC) gene and obesity in caucasian families

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Young-onset type 2 diabetes families are the major contributors to genetic loci in the Diabetes UK Warren 2 genome scan and identify putative novel loci on chromosomes 8q21, 21q22, and 22q11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A study of linkage and association of body mass index in the Old Order Amish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide scan for serum ghrelin detects linkage on chromosome 1p36 in Hispanic children: results from the Viva La Familia study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide scan for quantitative trait loci influencing LDL size and plasma triglyceride in familial hypertriglyceridemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide scan on plasma triglyceride and high density lipoprotein cholesterol levels, accounting for the effects of correlated quantitative phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide linkage analyses and candidate gene fine mapping for HDL3 cholesterol: the Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Evidence for bivariate linkage of obesity and HDL-C levels in the Framingham Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic Mexican Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide search for type 2 diabetes/impaired glucose homeostasis susceptibility genes in the Chinese: significant linkage to chromosome 6q21-q23 and chromosome 1q21-q24.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Subsets of Finns with high HDL to total cholesterol ratio show evidence for linkage to type 2 diabetes on chromosome 6q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Possible genomic imprinting of three human obesity-related genetic loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Variance-component analysis of obesity in type 2 diabetes confirms loci on chromosomes 1q and 11q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide scan for quantitative trait loci linked to obesity phenotypes among West Africans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study of selenium concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide association study of early spontaneous preterm delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study of biochemical traits in Korcula Island, Croatia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide association study of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Exploring the genetic basis of chronic periodontitis: a genome-wide association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study and meta-analysis identify ISL1 as genome-wide significant susceptibility gene for bladder exstrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association of lipid-lowering response to statins in combined study populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Discovery and refinement of loci associated with lipid levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Biological, clinical and population relevance of 95 loci for blood lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Common variants at 30 loci contribute to polygenic dyslipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

LDL-cholesterol concentrations: a genome-wide association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Joint influence of small-effect genetic variants on human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide association study identifies protein quantitative trait loci (pQTLs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Prognostic implications of genetic variants in advanced non-small cell lung cancer: a genome-wide association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Many sequence variants affecting diversity of adult human height

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Identification of ten loci associated with height highlights new biological pathways in human growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association study of height and body mass index in Australian twin families

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Hundreds of variants clustered in genomic loci and biological pathways affect human height

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Defining the role of common variation in the genomic and biological architecture of adult human height

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A novel common variant in DCST2 is associated with length in early life and height in adulthood

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide association with bone mass and geometry in the Framingham Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Chapter 11: Genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

The Genotype-Tissue Expression (GTEx) project

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Exome sequencing and subsequent association studies identify five amino acid-altering variants influencing human height.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Functional relevance of naturally occurring mutations in adhesion G protein-coupled receptor ADGRD1 (GPR133).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Mutant G-protein-coupled receptors as a cause of human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

G protein-coupled receptor mutations and human genetic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

G protein-coupled receptors: mutations and endocrine diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A novel mutation in CELSR1 is associated with hereditary lymphedema

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

G protein-coupled receptor-dependent development of human frontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Mutations in the VLGR1 gene implicate G-protein signaling in the pathogenesis of Usher syndrome type II

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Mutations of GPR126 are responsible for severe arthrogryposis multiplex congenita

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Vibratory Urticaria Associated with a Missense Variant in ADGRE2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gαq-p63RhoGEF-Rho GTPase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome scan for quantity of hand osteoarthritis: The Framingham study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide linkage analysis of bronchodilator responsiveness and post-bronchodilator spirometric phenotypes in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A Genome-Wide Search for Genes Involved in Type 2 Diabetes in a Recently Genetically Isolated Population From the Netherlands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genetic Loci Influencing Lung Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A quantitative trait locus influencing BMI maps to the region of the beta-3 adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Evidence for a Major Quantitative Trait Locus on Chromosome 17q21 Affecting Low-Density Lipoprotein Peak Particle Diameter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A Genome-Wide Scan for Abdominal Fat Assessed by Computed Tomography in the Quebec Family Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Evidence for a prostate cancer susceptibility locus on the X chromosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Combined Genome-Wide Scan for Prostate Cancer Susceptibility Genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Two-locus genome-wide linkage scan for prostate cancer susceptibility genes with an interaction effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Evidence From a Large U.K. Family Collection That Genes Influencing Age of Onset of Type 2 Diabetes Map to Chromosome 12p and to the MODY3/NIDDM2 Locus on 12q24

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

The adhesion GPCRs; gene repertoire, phylogeny and evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genomewide linkage analysis for prostate cancer susceptibility genes in families from Germany

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A locus influencing total serum cholesterol on chromosome 19p: results from an autosomal genomic scan of serum lipid concentrations in Pima Indians

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Finer linkage mapping of primary osteoarthritis susceptibility loci on chromosomes 4 and 16 in families with affected women

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A novel obesity locus on chromosome 4q: the Strong Heart Family Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genetic analysis of quantitative traits in highly ascertained samples: total serum IgE in families with asthma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genomic scan for genes affecting body composition before and after training in Caucasians from HERITAGE

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Identification of hypertension-related QTLs in African American sib pairs

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A Genomewide Screen in Multiplex Rheumatoid Arthritis Families Suggests Genetic Overlap with Other Autoimmune Diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Linkage analysis of asthma and atopy including models with genomic imprinting

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genomic searches for genes that influence atherosclerosis and its risk factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide linkage analysis for aggressive prostate cancer in Utah high-risk pedigrees

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide linkage analysis of blood pressure in Mexican Americans

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

An autosomal genomic scan for loci linked to type 2 diabetes in northern Han Chinese

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Linkage analysis of candidate genes as susceptibility loci for osteoarthritis-suggestive linkage of COL9A1 to female hip osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A genome scan for serum triglyceride in obese nuclear families

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Confirmation of the prostate cancer susceptibility locus HPCX in a set of 104 German prostate cancer families

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

Genome-wide Linkage Analysis for Severe Obesity in French Caucasians Finds Significant Susceptibility Locus on Chromosome 19q

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41523-9_9

10.1007/978-3-319-41523-9_9

31 March 2020

Identifiers

DOI

0 references

PubMed ID

27832489

1 reference

PubMed ID

27832489