Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals (Q38993086)

http://europepmc.org/abstract/PMC/5296221

22 June 2018

title

Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals (English)

1 reference

http://europepmc.org/abstract/PMC/5296221

22 June 2018

author

Benjamin Vitre

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Diana C Spierings

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Don W. Cleveland

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Floris Foijer

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

10

Diether Lambrechts

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Michelle S Levine

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Bjorn Bakker

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Bram Boeckx

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Julia Moyett

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

James Lu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Peter M Lansdorp

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Andrew J Holland

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

26 January 2017

1 reference

http://europepmc.org/abstract/PMC/5296221

22 June 2018

published in

Developmental Cell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

313-322.e5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

10 June 2020

cites work

1 reference

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22 June 2018

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Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer

22 June 2018

1 reference

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22 June 2018

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Epidermal development, growth control, and homeostasis in the face of centrosome amplification

22 June 2018

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Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma

22 June 2018

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p53 protects against genome instability following centriole duplication failure

22 June 2018

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Binding of STIL to Plk4 activates kinase activity to promote centriole assembly

22 June 2018

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Moesin is a major regulator of centrosome behavior in epithelial cells with extra centrosomes

22 June 2018

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22 June 2018

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22 June 2018

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Oncogene-like induction of cellular invasion from centrosome amplification

22 June 2018

1 reference

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Centrosome amplification causes microcephaly

22 June 2018

1 reference

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The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle

22 June 2018

1 reference

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Linking abnormal mitosis to the acquisition of DNA damage

22 June 2018

1 reference

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Supernumerary centrosomes nucleate extra cilia and compromise primary cilium signaling

22 June 2018

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DNA breaks and chromosome pulverization from errors in mitosis

22 June 2018

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A clinical overview of centrosome amplification in human cancers

22 June 2018

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Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations

22 June 2018

1 reference

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Intraflagellar transport: a new player at the immune synapse

22 June 2018

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Allele-specific copy number analysis of tumors

22 June 2018

1 reference

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Plk4 is required for cytokinesis and maintenance of chromosomal stability

22 June 2018

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22 June 2018

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Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

22 June 2018

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A mechanism linking extra centrosomes to chromosomal instability

22 June 2018

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Fast and accurate short read alignment with Burrows-Wheeler transform

22 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296221

Centrosome amplification can initiate tumorigenesis in flies.

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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SAK/PLK4 is required for centriole duplication and flagella development

22 June 2018

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22 June 2018

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Numerical and structural centrosome aberrations are an early and stable event in the adenoma-carcinoma sequence of colorectal carcinomas

22 June 2018

1 reference

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Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

22 June 2018

1 reference

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Spindle multipolarity is prevented by centrosomal clustering.

22 June 2018

1 reference

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Genomic instability in both wild-type and telomerase null MEFs

22 June 2018

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Abnormal centrosome amplification in the absence of p53.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296221

Mitosis in a cell with multiple centrioles

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296221

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296221

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296221

Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296221

Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis.

21 August 2018

1 reference

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A novel role for Plk4 in regulating cell spreading and motility.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296221

Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296221

Aneuploidy acts both oncogenically and as a tumor suppressor

21 August 2018

1 reference

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Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296221

Preparation, culture, and immortalization of mouse embryonic fibroblasts

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28132847

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Loss of Apc+ in intestinal adenomas from Min mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28132847

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.DEVCEL.2016.12.022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28132847%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference