Chronic centrosome amplification without tumorigenesis (Q36306041)

13 August 2017

Chronic centrosome amplification without tumorigenesis (English)

1 reference

13 August 2017

1

Benjamin Vitre

1 reference

13 August 2017

13

Elaine Fuchs

1 reference

13 August 2017

Don W Cleveland

14

0 references

Lino Tessarollo

11

object named as

Lino Tessarollo

1 reference

13 August 2017

Andrew J Holland

2

1 reference

13 August 2017

Anita Kulukian

3

1 reference

13 August 2017

Ofer Shoshani

4

1 reference

13 August 2017

Maretoshi Hirai

5

1 reference

13 August 2017

Yin Wang

6

1 reference

13 August 2017

Marcus Maldonado

7

1 reference

13 August 2017

Thomas Cho

8

1 reference

13 August 2017

Jihane Boubaker

9

1 reference

13 August 2017

Deborah A Swing

10

1 reference

13 August 2017

Sylvia M Evans

12

1 reference

13 August 2017

language of work or name

English

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publication date

2 November 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

13 August 2017

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13 August 2017

112

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13 August 2017

46

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13 August 2017

E6321-30

1 reference

describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4655534/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Epidermal development, growth control, and homeostasis in the face of centrosome amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

p53 protects against genome instability following centriole duplication failure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Moesin is a major regulator of centrosome behavior in epithelial cells with extra centrosomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Oncogene-like induction of cellular invasion from centrosome amplification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Centrosomes, chromosome instability (CIN) and aneuploidy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

A clinical overview of centrosome amplification in human cancers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

The causes and consequences of polyploidy in normal development and cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

The ploidy conveyor of mature hepatocytes as a source of genetic variation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Persistent telomere damage induces bypass of mitosis and tetraploidy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Centrioles, centrosomes, and cilia in health and disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

A mechanism linking extra centrosomes to chromosomal instability

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Mechanisms of procentriole formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Centrosome amplification can initiate tumorigenesis in flies.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

SAK/PLK4 is required for centriole duplication and flagella development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

The Polo kinase Plk4 functions in centriole duplication

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Centrosome amplification drives chromosomal instability in breast tumor development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

A new mathematical model for relative quantification in real-time RT-PCR

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/-) mouse tumors is carcinogen-and tissue-dependent

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Generalized lacZ expression with the ROSA26 Cre reporter strain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

'Green mice' as a source of ubiquitous green cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Abnormal centrosome amplification in the absence of p53.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Centrosome amplification causes microcephaly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

p53-Driven apoptosis limits centrosome amplification and genomic instability downstream of NPM1 phosphorylation

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4655534

RNA-dependent integrin alpha3 protein localization regulated by the Muscleblind-like protein MLP1

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1519388112

A role for endothelial NO synthase in LTP revealed by adenovirus-mediated inhibition and rescue.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1519388112

Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26578792

12 December 2020

inferred from PubMed ID database lookup

Centrosome abnormalities and chromosome instability occur together in pre-invasive carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26578792

12 December 2020

inferred from PubMed ID database lookup

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26578792

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1519388112

1 reference

13 August 2017

0 references

1 reference

13 August 2017

1 reference