Functional dynamics of deuterated β2 -adrenergic receptor in lipid bilayers revealed by NMR spectroscopy (Q38950368)

7 September 2017

Functional dynamics of deuterated β2 -adrenergic receptor in lipid bilayers revealed by NMR spectroscopy (English)

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7 September 2017

Yutaka Kofuku

1

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7 September 2017

Takumi Ueda

2

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7 September 2017

Junya Okude

3

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7 September 2017

Yutaro Shiraishi

4

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7 September 2017

Keita Kondo

5

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7 September 2017

Takuya Mizumura

6

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7 September 2017

Shiho Suzuki

7

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7 September 2017

Ichio Shimada

8

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7 September 2017

language of work or name

English

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publication date

3 October 2014

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Angewandte Chemie International Edition

7 September 2017

4

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based on heuristic

inferred from page(s)

published in

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volume

53

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7 September 2017

49

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7 September 2017

13376-13379

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describes a project that uses

7 September 2017

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Trends in the exploitation of novel drug targets

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The role of ligands on the equilibria between functional states of a G protein-coupled receptor

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The dynamic process of β(2)-adrenergic receptor activation

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Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR.

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Structural insights into agonist-induced activation of G-protein-coupled receptors

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Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins

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Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins.

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A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

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NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers.

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Functional equilibrium of the KcsA structure revealed by NMR.

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Cell-free expressed bacteriorhodopsin in different soluble membrane mimetics: biophysical properties and NMR accessibility.

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Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

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Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

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GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

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Modeling beta-adrenergic control of cardiac myocyte contractility in silico

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Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases

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Activation and deactivation kinetics of alpha 2A- and alpha 2C-adrenergic receptor-activated G protein-activated inwardly rectifying K+ channel currents

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Cell-signalling dynamics in time and space

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Quantification of receptor tyrosine kinase transactivation through direct dimerization and surface density measurements in single cells.

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21 January 2018

Identifiers

DOI

10.1002/ANIE.201406603

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7 September 2017

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