Loss of mitofusin 2 links beta-amyloid-mediated mitochondrial fragmentation and Cdk5-induced oxidative stress in neuron cells (Q38943638)

7 September 2017

title

Loss of mitofusin 2 links beta-amyloid-mediated mitochondrial fragmentation and Cdk5-induced oxidative stress in neuron cells (English)

1 reference

7 September 2017

6

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7 June 2020

author name string

Junghyung Park

1

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7 June 2020

Hoonsung Choi

2

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7 June 2020

Ju-Sik Min

3

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7 June 2020

Bokyung Kim

4

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7 June 2020

Sang-Rae Lee

5

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7 June 2020

Myung-Sook Choi

7

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7 June 2020

Kyu-Tae Chang

8

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7 June 2020

Dong-Seok Lee

9

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7 June 2020

language of work or name

English

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publication date

13 January 2015

1 reference

Journal of Neurochemistry

7 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359615%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

132

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7 June 2020

issue

6

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7 June 2020

page(s)

687-702

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A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy

7 June 2020

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Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

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Mfn2 modulates the UPR and mitochondrial function via repression of PERK

21 January 2018

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Loss of mitofusin 2 promotes endoplasmic reticulum stress

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The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

21 January 2018

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Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells.

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Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF.

21 January 2018

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Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit

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Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo

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Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease.

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Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction.

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Cdk5 is essential for synaptic vesicle endocytosis

21 January 2018

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An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator

21 January 2018

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p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

21 January 2018

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A beta oligomers - a decade of discovery

21 January 2018

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Cyclin-dependent kinase-5 prevents neuronal apoptosis through ERK-mediated upregulation of Bcl-2.

21 January 2018

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Endogenous overproduction of beta-amyloid induces tau hyperphosphorylation and decreases the solubility of tau in N2a cells

21 January 2018

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Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

21 January 2018

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Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

21 January 2018

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Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

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21 January 2018

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21 January 2018

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Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins

21 January 2018

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Amyloid precursor protein, heat-shock proteins, and Bcl-2 form a complex in mitochondria and modulate mitochondria function and apoptosis in N2a cells.

21 January 2018

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High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission

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The antioxidant enzyme peroxiredoxin and its protective role in neurological disorders

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Histone decacetylase inhibitors prevent mitochondrial fragmentation and elicit early neuroprotection against MPP+.

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Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis

21 January 2018

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