Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression (Q38936140)

7 September 2017

Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression (English)

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7 September 2017

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6

Sabine Werner

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7 September 2017

Serena Grossi

3

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Gabriele Fenini

object named as

Gabriele Fenini

5

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Lars E. French

object named as

Lars E French

7

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author name string

Martha Garstkiewicz

1

1 reference

7 September 2017

Gerhard E Strittmatter

2

1 reference

7 September 2017

Jennifer Sand

4

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7 September 2017

Hans-Dietmar Beer

8

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7 September 2017

language of work or name

English

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publication date

1 March 2017

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European Journal of Immunology

7 September 2017

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7 September 2017

47

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7 September 2017

806-817

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7 September 2017

5

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Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

7 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Toward clinical application of the Keap1-Nrf2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Roles nrf2 plays in myeloid cells and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Dimethyl fumarate : a Janus-faced substance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Inflammasomes in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Immunological and inflammatory functions of the interleukin-1 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Fumaric acid esters prevent the NLRP3 inflammasome-mediated and ATP-triggered pyroptosis of differentiated THP-1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Molecular basis of the Keap1-Nrf2 system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Nrf2 links epidermal barrier function with antioxidant defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

ASC speck formation as a readout for inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Sulforaphane ameliorates the development of experimental autoimmune encephalomyelitis by antagonizing oxidative stress and Th17-related inflammation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

BG-12 in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

A versatile viral system for expression and depletion of proteins in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

Improved vectors and genome-wide libraries for CRISPR screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

[New information about fumaric acid esters (Fumaderm): results of a workshop of experts]

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

7 January 2021

The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

7 January 2021

Caspase-1 activity is required for UVB-induced apoptosis of human keratinocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

7 January 2021

Caspase-4 is required for activation of inflammasomes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201646665

7 January 2021

Identifiers

DOI

10.1002/EJI.201646665

1 reference

7 September 2017

1 reference