KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination (Q38916626)

7 September 2017

KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination (English)

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Influenza virus NS1A binding protein

7 September 2017

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negative regulation of protein ubiquitination

GOA release 2020-03-11

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GOA release 2020-03-11

protein ubiquitination

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H Y Chen

1

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7 September 2017

J Y Hu

2

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7 September 2017

T H Chen

3

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7 September 2017

Y C Lin

4

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7 September 2017

X Liu

5

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7 September 2017

M Y Lin

6

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7 September 2017

Y D Lang

7

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7 September 2017

Y Yen

8

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7 September 2017

R H Chen

9

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7 September 2017

language of work or name

English

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publication date

26 January 2015

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7 September 2017

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34

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40

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5141-5151

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https://scigraph.springernature.com/pub.10.1038/onc.2014.435

7 September 2017

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The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses

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A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression

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BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

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DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals

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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

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PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function

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Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein

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USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.

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NS1-Binding protein (NS1-BP): a novel human protein that interacts with the influenza A virus nonstructural NS1 protein is relocalized in the nuclei of infected cells

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25619834

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A kelch family protein Nd1-L functions as a metastasis suppressor in cancer cells via Rho family proteins mediated mechanism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25619834

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.435

1 reference

Dimensions Publication ID

7 September 2017

0 references

1 reference