High-glucose-increased expression and activation of NADPH oxidase in human vascular smooth muscle cells is mediated by 4-hydroxynonenal-activated PPARα and PPARβ/δ. (Q38905577)

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English	High-glucose-increased expression and activation of NADPH oxidase in human vascular smooth muscle cells is mediated by 4-hydroxynonenal-activated PPARα and PPARβ/δ.	scientific article

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1 March 2020

High-glucose-increased expression and activation of NADPH oxidase in human vascular smooth muscle cells is mediated by 4-hydroxynonenal-activated PPARα and PPARβ/δ (English)

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author name string

Adrian Manea

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Simona-Adriana Manea

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Andra Todirita

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Irina Cristina Albulescu

4

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Monica Raicu

5

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Maya Simionescu

7

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27 February 2015

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Cell and Tissue Research

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361

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2

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593-604

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https://scigraph.springernature.com/pub.10.1007/s00441-015-2120-0

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Gemfibrozil decreases atherosclerosis in experimental diabetes in association with a reduction in oxidative stress and inflammation

1 reference

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21 January 2018

Role of lipid peroxidation and PPAR-δ in amplifying glucose-stimulated insulin secretion

1 reference

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21 January 2018

Signaling properties of 4-hydroxyalkenals formed by lipid peroxidation in diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00441-015-2120-0

21 January 2018

The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta)

1 reference

https://api.crossref.org/works/10.1007%2FS00441-015-2120-0

21 January 2018

NOX and inflammation in the vascular adventitia

1 reference

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21 January 2018

The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle

1 reference

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21 January 2018

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

1 reference

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21 January 2018

Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signalling

1 reference

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21 January 2018

PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a

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21 January 2018

PPAR agonists: multimodal drugs for the treatment of type-2 diabetes

1 reference

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21 January 2018

Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.

1 reference

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21 January 2018

NADPH oxidases as therapeutic targets in ischemic stroke.

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Rapid increase in serum lipid peroxide 4-hydroxynonenal (HNE) through monocyte NADPH oxidase in early endo-toxemia

1 reference

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21 January 2018

NOX enzymes as drug targets

1 reference

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21 January 2018

Peroxisome proliferator-activated receptor-alpha gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice

1 reference

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21 January 2018

Activation of NAD(P)H oxidase by lipid hydroperoxides: mechanism of oxidant-mediated smooth muscle cytotoxicity.

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21 January 2018

NADPH oxidase-derived reactive oxygen species: involvement in vascular physiology and pathology

1 reference

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21 January 2018

Nox enzymes and oxidative stress in atherosclerosis

1 reference

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21 January 2018

AP-1-dependent transcriptional regulation of NADPH oxidase in human aortic smooth muscle cells: role of p22phox subunit.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-015-2120-0

21 January 2018

Jak/STAT signaling pathway regulates nox1 and nox4-based NADPH oxidase in human aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-015-2120-0

21 January 2018

Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-015-2120-0

21 January 2018

Positive regulation of NADPH oxidase 5 by proinflammatory-related mechanisms in human aortic smooth muscle cells

1 reference

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21 January 2018

High glucose-induced increased expression of endothelin-1 in human endothelial cells is mediated by activated CCAAT/enhancer-binding proteins

1 reference

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21 January 2018

C/EBP transcription factors regulate NADPH oxidase in human aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-015-2120-0

21 January 2018

PPARbeta/delta regulates the human SIRT1 gene transcription via Sp1.

1 reference

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21 January 2018

The PPAR-RXR transcriptional complex in the vasculature: energy in the balance

1 reference

https://api.crossref.org/works/10.1007%2FS00441-015-2120-0

21 January 2018

Signaling and cytotoxic functions of 4-hydroxyalkenals.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-015-2120-0

21 January 2018

The natural protective mechanism against hyperglycemia in vascular endothelial cells: roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor delta

1 reference

https://api.crossref.org/works/10.1007%2FS00441-015-2120-0

21 January 2018

PPARs and molecular mechanisms of transrepression

1 reference

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21 January 2018

Dietary n-6 and n-3 polyunsaturated fatty acids: from biochemistry to clinical implications in cardiovascular prevention.

1 reference

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21 January 2018

Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition

1 reference

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21 January 2018

Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy

1 reference

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21 January 2018

Oxidative stress, Nox isoforms and complications of diabetes--potential targets for novel therapies

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21 January 2018

Peroxisome proliferator-activated receptor alpha agonists enhance cardiomyogenesis of mouse ES cells by utilization of a reactive oxygen species-dependent mechanism.

1 reference

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21 January 2018

PPAR agonists and the metabolic syndrome

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Therapeutic roles of peroxisome proliferator-activated receptor agonists

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21 January 2018

Apocynin: molecular aptitudes

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Peroxisome proliferator-activated receptor alpha induces NADPH oxidase activity in macrophages, leading to the generation of LDL with PPAR-alpha activation properties

1 reference

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21 January 2018

The effects of low density lipoproteins modified by incubation with chondroitin 6-sulfate on human aortic smooth muscle cells

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21 January 2018

Absence of peroxisome proliferator-activated receptor-alpha abolishes hypertension and attenuates atherosclerosis in the Tsukuba hypertensive mouse

1 reference

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21 January 2018

Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II.

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21 January 2018

Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase

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21 January 2018

Peroxisome proliferator-activated receptor alpha: friend or foe?

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5-Lipoxygenase plays an essential role in 4-HNE-enhanced ROS production in murine macrophages via activation of NADPH oxidase

1 reference

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Polymorphisms and promoter overactivity of the p22(phox) gene in vascular smooth muscle cells from spontaneously hypertensive rats.

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Inflammation, dyslipidaemia, diabetes and PPars: pharmacological interest of dual PPARalpha and PPARgamma agonists

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NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

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10.1007/S00441-015-2120-0

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1 March 2020

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