Histone acetylation: novel target for the treatment of acute lymphoblastic leukemia (Q26778780)

2

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Andres Stucky

3

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Xue-Lian Chen

4

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Michael F Press

5

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Xi Zhang

https://scigraph.springernature.com/pub.10.1186/s13148-015-0151-8

6

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language of work or name

English

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publication date

2015

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1 reference

7

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page(s)

117

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issue

1

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exact match

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cites work

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Translating the Histone Code

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Regulation of chromatin structure by site-specific histone H3 methyltransferases

7 April 2017

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Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction

7 April 2017

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Cancer epigenetics drug discovery and development: the challenge of hitting the mark

7 April 2017

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

7 April 2017

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Structure of histone acetyltransferases

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Signaling to chromatin through histone modifications

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The bromodomain: a chromatin-targeting module?

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Targeting bromodomains: epigenetic readers of lysine acetylation

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Regulation of nucleosome dynamics by histone modifications

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Co-regulation of histone-modifying enzymes in cancer

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Histone variants--ancient wrap artists of the epigenome

7 April 2017

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Acetylation of non-histone proteins modulates cellular signalling at multiple levels

7 April 2017

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The epigenomics of cancer

7 April 2017

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The cancer epigenome--components and functional correlates

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Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

7 April 2017

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Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes

7 April 2017

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Histone acetylation and transcriptional regulatory mechanisms

7 April 2017

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A unique chromatin signature uncovers early developmental enhancers in humans

7 April 2017

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Charting histone modifications and the functional organization of mammalian genomes

7 April 2017

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Linking DNA methylation and histone modification: patterns and paradigms

7 April 2017

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

7 April 2017

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Histone deacetylases and mechanisms of regulation of gene expression

7 April 2017

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Effect of valproic acid on the proliferation and apoptosis of the human melanoma G-361 cell line

28 September 2017

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Epigenetics in T-cell acute lymphoblastic leukemia

28 September 2017

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Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

28 September 2017

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The growing landscape of lysine acetylation links metabolism and cell signalling

28 September 2017

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HDAC-inhibition counteracts everolimus resistance in renal cell carcinoma in vitro by diminishing cdk2 and cyclin A.

28 September 2017

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Understanding the relationship between DNA methylation and histone lysine methylation

28 September 2017

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Suberoylanilide hydroxamic acid (SAHA) causes tumor growth slowdown and triggers autophagy in glioblastoma stem cells.

28 September 2017

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The expression of histone deacetylase 4 is associated with prednisone poor-response in childhood acute lymphoblastic leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634719

Relapsed childhood acute lymphoblastic leukaemia

28 September 2017

1 reference

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Differential mRNA expression levels of human histone-modifying enzymes in normal karyotype B cell pediatric acute lymphoblastic leukemia

28 September 2017

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Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?

28 September 2017

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A phase I pharmacokinetic and pharmacodynamic study of CHR-3996, an oral class I selective histone deacetylase inhibitor in refractory solid tumors

28 September 2017

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CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia

28 September 2017

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Emerging pharmacotherapies for adult patients with acute lymphoblastic leukemia

28 September 2017

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HDAC modulation and cell death in the clinic

28 September 2017

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Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia.

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4634719

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

28 September 2017

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Deacetylation of nonhistone proteins by HDACs and the implications in cancer

28 September 2017

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HDAC inhibitors potentiate the activity of the BCR/ABL kinase inhibitor KW-2449 in imatinib-sensitive or -resistant BCR/ABL+ leukemia cells in vitro and in vivo

28 September 2017

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Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs.

28 September 2017

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CREBBP mutations in relapsed acute lymphoblastic leukaemia

28 September 2017

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The role of HDACs inhibitors in childhood and adolescence acute leukemias

28 September 2017

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Valproic acid perturbs hematopoietic homeostasis by inhibition of erythroid differentiation and activation of the myelo-monocytic pathway

28 September 2017

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Targeting paediatric acute lymphoblastic leukaemia: novel therapies currently in development

28 September 2017

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Histone H4 acetylation by immunohistochemistry and prognosis in newly diagnosed adult acute lymphoblastic leukemia (ALL) patients

28 September 2017

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Efficacy of MK-0457 and in combination with vorinostat against Philadelphia chromosome positive acute lymphoblastic leukemia cells

28 September 2017

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Tuning acetylated chromatin with HAT inhibitors: a novel tool for therapy

28 September 2017

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Romidepsin for the treatment of cutaneous T-cell lymphoma

28 September 2017

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Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy

28 September 2017

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Initial testing (stage 1) of vorinostat (SAHA) by the pediatric preclinical testing program.

28 September 2017

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Histone deacetylase inhibitors as anti-neoplastic agents.

28 September 2017

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Anti-leukemic activity of valproic acid and imatinib mesylate on human Ph+ ALL and CML cells in vitro

28 September 2017

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Development of vorinostat: current applications and future perspectives for cancer therapy

28 September 2017

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The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells

28 September 2017

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Modulation of TRAIL-induced apoptosis by HDAC inhibitors

28 September 2017

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Histone deacetylase inhibitors: overview and perspectives

28 September 2017

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Histone deacetylase inhibitors: molecular mechanisms of action

28 September 2017

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Vorinostat: a new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma

28 September 2017

1 reference

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A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies

28 September 2017

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Antileukemia activity of the combination of 5-aza-2'-deoxycytidine with valproic acid

28 September 2017

1 reference

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Chromatin modifying activity of leukaemia associated fusion proteins

28 September 2017

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28 September 2017

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Use of a novel histone deacetylase inhibitor to induce apoptosis in cell lines of acute lymphoblastic leukemia.

28 September 2017

1 reference

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The histone deacetylase inhibitor AN-9 has selective toxicity to acute leukemia and drug-resistant primary leukemia and cancer cell lines

28 September 2017

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Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP

28 September 2017

1 reference

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Phase I study of chidamide (CS055/HBI-8000), a new histone deacetylase inhibitor, in patients with advanced solid tumors and lymphomas

28 September 2017

1 reference

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Potentiation of reactive oxygen species is a marker for synergistic cytotoxicity of MS-275 and 5-azacytidine in leukemic cells

31 May 2018

1 reference

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Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor

31 May 2018

1 reference

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The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.

31 May 2018

1 reference

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GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia

31 May 2018

1 reference

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Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13148-015-0151-8

Histone H4 acetylation by immunohistochemistry and prognosis in relapsed acute lymphocytic leukaemia (ALL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13148-015-0151-8

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13148-015-0151-8

Valproic acid in the complex therapy of malignant tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13148-015-0151-8

Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13148-015-0151-8

Synergistic activity of bortezomib and HDACi in preclinical models of B-cell precursor acute lymphoblastic leukemia via modulation of p53, PI3K/AKT, and NF-κB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13148-015-0151-8

The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.

21 January 2018

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https://api.crossref.org/works/10.1186%2FS13148-015-0151-8

Cancer epigenetics: new therapies and new challenges.

21 January 2018

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https://api.crossref.org/works/10.1186%2FS13148-015-0151-8

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

21 January 2018

1 reference

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Impact of the putative differentiating agent sodium phenylbutyrate on myelodysplastic syndromes and acute myeloid leukemia

28 November 2018

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Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome

28 November 2018

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12 December 2020

ICER expression inhibits leukemia phenotype and controls tumor progression

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12 December 2020

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo

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12 December 2020

DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: insights into CpG island methylator phenotype in T-ALL

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12 December 2020

HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway

1 reference

12 December 2020

Histone deacetylase inhibitors have antitumor activity in two NOD/SCID mouse models of B-cell precursor childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Increased activity of histone deacetylases in childhood acute lymphoblastic leukaemia and acute myeloid leukaemia: support for histone deacetylase inhibitors as antileukaemic agents

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12 December 2020

[Effect of valproic acid sodium on proliferation and apoptosis of acute T-lymphoblastic leukemia Jurkat cells]

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12 December 2020

Chemical studies of histone acetylation. The distribution of epsilon-N-acetyllysine in calf thymus histones

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12 December 2020

PI3-K/Akt-dependent activation of cAMP-response element-binding (CREB) protein in Jurkat T leukemia cells treated with TRAIL

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12 December 2020