HMGA2 as a potential molecular target in KMT2A-AFF1-positive infant acute lymphoblastic leukaemia (Q38832808)

6 September 2017

HMGA2 as a potential molecular target in KMT2A-AFF1-positive infant acute lymphoblastic leukaemia (English)

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6 September 2017

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Zhouying Wu

1

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6 September 2017

Minenori Eguchi-Ishimae

2

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6 September 2017

Chihiro Yagi

3

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6 September 2017

Hidehiko Iwabuki

4

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6 September 2017

Wenming Gao

5

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6 September 2017

Hisamichi Tauchi

6

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6 September 2017

Takeshi Inukai

7

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6 September 2017

Kanji Sugita

8

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6 September 2017

Eiichi Ishii

9

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6 September 2017

Mariko Eguchi

10

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6 September 2017

language of work or name

English

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publication date

25 September 2015

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British Journal of Haematology

6 September 2017

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6 September 2017

171

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6 September 2017

5

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6 September 2017

818-829

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The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

6 September 2017

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Regulation of HMGIC expression: an architectural transcription factor involved in growth control and development

21 January 2018

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Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2

21 January 2018

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Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia

21 January 2018

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HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB

21 January 2018

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The Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells

21 January 2018

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Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

21 January 2018

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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

21 January 2018

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Downregulation of HMGA2 by the pan-deacetylase inhibitor panobinostat is dependent on hsa-let-7b expression in liver cancer cell lines.

21 January 2018

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The small oligomerization domain of gephyrin converts MLL to an oncogene

21 January 2018

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Epigenetics in clinical practice: the examples of azacitidine and decitabine in myelodysplasia and acute myeloid leukemia

21 January 2018

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21 January 2018

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Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

21 January 2018

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HMGA2, microRNAs, and stem cell aging

21 January 2018

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Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferative neoplasms.

21 January 2018

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Gene expressions of HMGI-C and HMGI(Y) are associated with stage and metastasis in colorectal cancer.

21 January 2018

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Expression of thrombopoietin receptor and its functional role in human B-precursor leukemia cells with 11q23 translocation or Philadelphia chromosome.

21 January 2018

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Leukemic cells with 11q23 translocations express granulocyte colony-stimulating factor (G-CSF) receptor and their proliferation is stimulated with G-CSF.

21 January 2018

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DDB1-CUL4 and MLL1 mediate oncogene-induced p16INK4a activation

21 January 2018

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Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice.

21 January 2018

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The tumor suppressor microRNA let-7 represses the HMGA2 oncogene

21 January 2018

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G-749, a novel FLT3 kinase inhibitor, can overcome drug resistance for the treatment of acute myeloid leukemia

21 January 2018

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The ubiquitin ligase human TRIM71 regulates let-7 microRNA biogenesis via modulation of Lin28B protein

21 January 2018

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An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis

21 January 2018

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Oncogenic NRAS, required for pathogenesis of embryonic rhabdomyosarcoma, relies upon the HMGA2-IGF2BP2 pathway

21 January 2018

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RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence.

21 January 2018

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Mechanisms of leukemogenesis by MLL fusion proteins

21 January 2018

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Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

21 January 2018

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Inhibition of high-mobility-group A2 protein binding to DNA by netropsin: a biosensor-surface plasmon resonance assay

21 January 2018

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Clinical development of demethylating agents in hematology

21 January 2018

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Suppression of the let-7b microRNA pathway by DNA hypermethylation in infant acute lymphoblastic leukemia with MLL gene rearrangements.

21 January 2018

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Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression

21 January 2018

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High mobility group a proteins as tumor markers

21 January 2018

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Hoechst 33258, distamycin A, and high mobility group protein I (HMG-I) compete for binding to mouse satellite DNA.

21 January 2018

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

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Sp1 and CTF/NF-1 transcription factors are involved in the basal expression of the Hmgi-c proximal promoter

21 January 2018

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Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting.

21 January 2018

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MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia

21 January 2018

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Lin28: primal regulator of growth and metabolism in stem cells

21 January 2018

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Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia

21 January 2018

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Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants

21 January 2018

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HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis.

21 January 2018

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Ink4a/Arf regulation by let-7b and Hmga2: a genetic pathway governing stem cell aging.

21 January 2018

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21 January 2018

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Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.

21 January 2018

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Overexpression of HMGA2 promotes metastasis and impacts survival of colorectal cancers.

21 January 2018

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RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction

21 January 2018

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Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer

21 January 2018

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Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia

21 January 2018

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Genomic structure and expression of the murine Hmgi-c gene

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/BJH.13763

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6 September 2017

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