The Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells (Q38314511)

2 September 2017

The Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells (English)

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2 September 2017

14

Connie J Eaves

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2 September 2017

4

David J H F Knapp

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2 September 2017

Michael R Copley

1

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2 September 2017

Sonja Babovic

2

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2 September 2017

Claudia Benz

3

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2 September 2017

Philip A Beer

5

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2 September 2017

David G Kent

6

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2 September 2017

Stefan Wohrer

7

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2 September 2017

David Q Treloar

8

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2 September 2017

Christopher Day

9

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2 September 2017

Keegan Rowe

10

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2 September 2017

Heidi Mader

11

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2 September 2017

Florian Kuchenbauer

12

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2 September 2017

R Keith Humphries

13

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2 September 2017

30 June 2013

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2 September 2017

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2 September 2017

15

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2 September 2017

916-925

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2 September 2017

8

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https://scigraph.springernature.com/pub.10.1038/ncb2783

2 September 2017

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cites work

In Vivo Transduction by Intravenous Injection of a Lentiviral Vector Expressing Human ADA into Neonatal ADA Gene Knockout Mice: A Novel Form of Enzyme Replacement Therapy for ADA Deficiency

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12 December 2020

Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs

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12 December 2020

Mini-mouse: disruption of the pygmy locus in a transgenic insertional mutant

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12 December 2020

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

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12 December 2020

Selective blockade of microRNA processing by Lin28

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12 December 2020

Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival

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12 December 2020

The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA

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12 December 2020

The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts

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12 December 2020

Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells

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12 December 2020

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

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12 December 2020

Somatomedin activity in sera of genetically small mice

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12 December 2020

Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression

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12 December 2020

Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria

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12 December 2020

Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties

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12 December 2020

Molecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH).

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12 December 2020

High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells

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12 December 2020

Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

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12 December 2020

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

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12 December 2020

Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivo

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12 December 2020

Relative to adult marrow, fetal liver repopulates nearly five times more effectively long-term than short-term

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12 December 2020

The placenta is a niche for hematopoietic stem cells

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12 December 2020

Mini-mouse: phenotypic characterization of a transgenic insertional mutant allelic to pygmy

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12 December 2020

Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2

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12 December 2020

The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation.

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12 December 2020

Competitivein vivo proliferation of foetal and adult haematopoietic cells in lethally irradiated mice

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12 December 2020

An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis

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12 December 2020

Developmental decline in neuronal regeneration by the progressive change of two intrinsic timers

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12 December 2020

A common variant of HMGA2 is associated with adult and childhood height in the general population

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12 December 2020

Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy

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12 December 2020

3'UTR-truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growth advantage at the level of HSC in mice

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12 December 2020

C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence

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12 December 2020

Developmental switch of mouse hematopoietic stem cells from fetal to adult type occurs in bone marrow after birth

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12 December 2020

The murine placenta contains hematopoietic stem cells within the vascular labyrinth region.

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12 December 2020

Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.

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12 December 2020

Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs): role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver

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12 December 2020

The emergence of definitive hematopoietic stem cells in the mammal

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12 December 2020

The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche

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12 December 2020

Molecular basis of the little mouse phenotype and implications for cell type-specific growth

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12 December 2020

Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.

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12 December 2020

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

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12 December 2020

The total marrow mass of the mouse: a simplified method of measurement

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12 December 2020

Refinement of the 12q14 microdeletion syndrome: primordial dwarfism and developmental delay with or without osteopoikilosis

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12 December 2020

ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

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12 December 2020

The purification and characterization of fetal liver hematopoietic stem cells.

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12 December 2020

Expansion in vitro of adult murine hematopoietic stem cells with transplantable lympho-myeloid reconstituting ability

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12 December 2020

Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential.

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12 December 2020

Long-term propagation of distinct hematopoietic differentiation programs in vivo

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12 December 2020

Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect

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12 December 2020

Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis

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12 December 2020

The 12q14 microdeletion syndrome: six new cases confirming the role of HMGA2 in growth

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12 December 2020

Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C

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12 December 2020

Expansion of hematopoietic stem cells in the developing liver of a mouse embryo

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12 December 2020

Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells.

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12 December 2020

Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation

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12 December 2020

Dynamics of gene-modified progenitor cells analyzed by tracking retroviral integration sites in a human SCID-X1 gene therapy trial

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12 December 2020

Roles of HMGA proteins in cancer

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12 December 2020

Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1.

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12 December 2020

Serum and pituitary concentrations of growth hormone and prolactin in pygmy mice

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12 December 2020

HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB

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12 December 2020

Identifiers

DOI

10.1038/NCB2783

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Dimensions Publication ID

2 September 2017

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