IGF/STAT3/NANOG/Slug Signaling Axis Simultaneously Controls Epithelial-Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer (Q38796942)

6 September 2017

IGF/STAT3/NANOG/Slug Signaling Axis Simultaneously Controls Epithelial-Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer (English)

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6 September 2017

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Chao Yao

1

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6 September 2017

Li Su

2

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6 September 2017

Juanjuan Shan

3

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6 September 2017

Chuanlin Zhu

4

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6 September 2017

Limei Liu

5

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6 September 2017

Chungang Liu

6

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6 September 2017

Yanmin Xu

7

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6 September 2017

Zhi Yang

8

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6 September 2017

Xiuwu Bian

9

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6 September 2017

Jimin Shao

10

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6 September 2017

Jianming Li

11

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6 September 2017

Maode Lai

12

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6 September 2017

Junjie Shen

13

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6 September 2017

Cheng Qian

14

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6 September 2017

language of work or name

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3 February 2016

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6 September 2017

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6 September 2017

34

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6 September 2017

4

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6 September 2017

820-831

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Cancer metastasis: building a framework

6 September 2017

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The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

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Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

21 January 2018

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Nanog regulates self-renewal of cancer stem cells through the insulin-like growth factor pathway in human hepatocellular carcinoma

21 January 2018

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Cancer stem cells: impact, heterogeneity, and uncertainty

21 January 2018

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Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.

21 January 2018

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NANOG modulates stemness in human colorectal cancer

21 January 2018

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Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms

21 January 2018

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Oct-4 and Nanog promote the epithelial-mesenchymal transition of breast cancer stem cells and are associated with poor prognosis in breast cancer patients

21 January 2018

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NANOG promotes liver cancer cell invasion by inducing epithelial-mesenchymal transition through NODAL/SMAD3 signaling pathway

21 January 2018

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Snail regulates Nanog status during the epithelial-mesenchymal transition via the Smad1/Akt/GSK3β signaling pathway in non-small-cell lung cancer

21 January 2018

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Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer

21 January 2018

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Fibulin-3-mediated inhibition of epithelial-to-mesenchymal transition and self-renewal of ALDH+ lung cancer stem cells through IGF1R signaling

21 January 2018

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Histone deacetylase 3 participates in self-renewal of liver cancer stem cells through histone modification

21 January 2018

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Association of insulin-like growth factor-I receptor polymorphism with colorectal cancer development.

21 January 2018

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β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma

21 January 2018

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STAT3 is necessary for proliferation and survival in colon cancer-initiating cells

21 January 2018

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Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition

21 January 2018

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CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation

21 January 2018

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Snail/slug family of repressors: slowly going into the fast lane of development and cancer

21 January 2018

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The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells.

21 January 2018

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High motility of triple-negative breast cancer cells is due to repression of plakoglobin gene by metastasis modulator protein SLUG.

21 January 2018

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The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

21 January 2018

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Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog

21 January 2018

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Functional evidence that the self-renewal gene NANOG regulates human tumor development

21 January 2018

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TGFbeta signalling: a complex web in cancer progression

21 January 2018

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Tgf-beta signaling alterations and colon cancer

21 January 2018

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SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer

21 January 2018

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Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition

21 January 2018

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21 January 2018

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Insulin receptor isoform switching in intestinal stem cells, progenitors, differentiated lineages and tumors: evidence that IR-B limits proliferation

21 January 2018

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STAT3 expression, molecular features, inflammation patterns, and prognosis in a database of 724 colorectal cancers

21 January 2018

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Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth

21 January 2018

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Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer.

21 January 2018

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Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells

21 January 2018

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Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.

21 January 2018

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Predicting distinct organization of transcription factor binding sites on the promoter regions: a new genome-based approach to expand human embryonic stem cell regulatory network.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.2320

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6 September 2017

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