Modulation of Neuroinflammation in the Central Nervous System: Role of Chemokines and Sphingolipids (Q38774697)

6 September 2017

Modulation of Neuroinflammation in the Central Nervous System: Role of Chemokines and Sphingolipids (English)

1 reference

6 September 2017

0 references

1 reference

Laura Guarnaccia

2

0 references

Giovanni Marfia

Giovanni Marfia

8

0 references

Rolando Campanella

Rolando Campanella

5

0 references

Stefania Elena Navone

Stefania E Navone

4

0 references

Roberta Gualtierotti

Roberta Gualtierotti

1

0 references

Laura Riboni

Laura Riboni

6

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author name string

Matteo Beretta

3

1 reference

6 September 2017

Paolo Rampini

7

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6 September 2017

language of work or name

English

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publication date

4 January 2017

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6 September 2017

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6 September 2017

34

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6 September 2017

396-420

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6 September 2017

2

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https://scigraph.springernature.com/pub.10.1007/s12325-016-0474-7

6 September 2017

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A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors.

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CXC chemokines interleukin-8 (IL-8) and growth-related gene product alpha (GROalpha) modulate Purkinje neuron activity in mouse cerebellum.

21 January 2018

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Beyond neurons: evidence that immune and glial cells contribute to pathological pain states

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Molecular inflammatory mediators in peripheral nerve degeneration and regeneration.

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Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia.

21 January 2018

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Microglial activation state and lysophospholipid acid receptor expression

21 January 2018

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The Adipose Mesenchymal Stem Cell Secretome Inhibits Inflammatory Responses of Microglia: Evidence for an Involvement of Sphingosine-1-Phosphate Signalling.

21 January 2018

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Anti-inflammatory mechanism of exogenous C2 ceramide in lipopolysaccharide-stimulated microglia

21 January 2018

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Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy

21 January 2018

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Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors.

21 January 2018

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Ceramide in primary astrocytes from cerebellum: metabolism and role in cell proliferation

21 January 2018

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Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes

21 January 2018

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Sphingosine kinase 1/S1P receptor signaling axis controls glial proliferation in mice with Sandhoff disease.

21 January 2018

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Gangliosides trigger inflammatory responses via TLR4 in brain glia

21 January 2018

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JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells

21 January 2018

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Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin

21 January 2018

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Second generation S1P pathway modulators: research strategies and clinical developments.

21 January 2018

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Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?

21 January 2018

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Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

21 January 2018

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Th17 Cells Pathways in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders: Pathophysiological and Therapeutic Implications

21 January 2018

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Characteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis

21 January 2018

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Expression of chemokine receptors on peripheral blood lymphocytes in multiple sclerosis and neuromyelitis optica

21 January 2018

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C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

21 January 2018

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Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

21 January 2018

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The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

21 January 2018

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New insights into the role of stromal cell-derived factor 1 (SDF-1/CXCL12) in the pathophysiology of multiple sclerosis.

21 January 2018

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Monocyte migration and LFA-1-mediated attachment to brain microvascular endothelia is regulated by SDF-1 alpha through Lyn kinase

21 January 2018

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Astrocytes produce dendritic cell-attracting chemokines in vitro and in multiple sclerosis lesions

21 January 2018

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Targeting CXCL13 During Neuroinflammation

21 January 2018

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Cerebrospinal fluid IL-12p40, CXCL13 and IL-8 as a combinatorial biomarker of active intrathecal inflammation

21 January 2018

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Aberrant upregulation of astroglial ceramide potentiates oligodendrocyte injury.

21 January 2018

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Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs

21 January 2018

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Sphingosine 1-phosphate (S1P): Physiology and the effects of S1P receptor modulation.

21 January 2018

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Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis

21 January 2018

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Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation

21 January 2018

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Ponesimod, a selective S1P1 receptor modulator: a potential treatment for multiple sclerosis and other immune-mediated diseases

21 January 2018

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FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

21 January 2018

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Safety and efficacy of the selective sphingosine 1-phosphate receptor modulator ozanimod in relapsing multiple sclerosis (RADIANCE): a randomised, placebo-controlled, phase 2 trial

21 January 2018

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International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

21 January 2018

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Current concept of neuromyelitis optica (NMO) and NMO spectrum disorders.

21 January 2018

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Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6

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Relationship between cerebrospinal fluid biomarkers for inflammation, demyelination and neurodegeneration in acute optic neuritis

21 January 2018

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Development of extensive brain lesions following fingolimod (FTY720) treatment in a patient with neuromyelitis optica spectrum disorder.

21 January 2018

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Fingolimod-induced leukoencephalopathy in a patient with neuromyelitis optica spectrum disorder.

21 January 2018

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Systemic lupus erythematosus.

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Pathogenesis, diagnosis and management of neuropsychiatric SLE manifestations

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Cytokines and chemokines in neuropsychiatric syndromes of systemic lupus erythematosus

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Pathogenesis of neuropsychiatric systemic lupus erythematosus and potential biomarkers

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Increased levels of proinflammatory cytokines and nitric oxide metabolites in neuropsychiatric lupus erythematosus

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Raised monocyte chemotactic protein-1 (MCP-1)/CCL2 in cerebrospinal fluid of patients with neuropsychiatric lupus

21 January 2018

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Potent induction of IFN-alpha and chemokines by autoantibodies in the cerebrospinal fluid of patients with neuropsychiatric lupus

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Cutting edge: Human Th17 cells are identified as bearing CCR2+CCR5- phenotype.

21 January 2018

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IL-6, IL-8, IP-10, MCP-1 and G-CSF are significantly increased in cerebrospinal fluid but not in sera of patients with central neuropsychiatric lupus erythematosus

21 January 2018

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Sphingosine kinase and sphingosine-1-phosphate: regulators in autoimmune and inflammatory disease

21 January 2018

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Increased survival and reduced renal injury in MRL/lpr mice treated with a novel sphingosine-1-phosphate receptor agonist

21 January 2018

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FTY720 exerts a survival advantage through the prevention of end-stage glomerular inflammation in lupus-prone BXSB mice

21 January 2018

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Inhibition of sphingosine kinase-2 in a murine model of lupus nephritis

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The Role of Inflammatory Mediators in the Pathogenesis of Alzheimer's Disease

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The role of microglia in amyloid clearance from the AD brain

21 January 2018

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Phagocytic clearance in neurodegeneration

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In vivo structure/function and expression analysis of the CX3C chemokine fractalkine

21 January 2018

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CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.

21 January 2018

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21 January 2018

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ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function

21 January 2018

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Changes in the levels of plasma soluble fractalkine in patients with mild cognitive impairment and Alzheimer's disease.

21 January 2018

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Changes in the expression of genes related to neuroinflammation over the course of sporadic Alzheimer's disease progression: CX3CL1, TREM2, and PPARγ.

21 January 2018

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Serum MCP-1 levels are increased in mild cognitive impairment and mild Alzheimer's disease

21 January 2018

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Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.

21 January 2018

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CCL2 disrupts the adherens junction: implications for neuroinflammation

21 January 2018

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Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

21 January 2018

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Sphingolipids: critical players in Alzheimer's disease

21 January 2018

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Oxidative stress resistance in hippocampal cells is associated with altered membrane fluidity and enhanced nonamyloidogenic cleavage of endogenous amyloid precursor protein.

21 January 2018

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Altered lipid composition in cortical lipid rafts occurs at early stages of sporadic Alzheimer's disease and facilitates APP/BACE1 interactions.

21 January 2018

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Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease

21 January 2018

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Exosome reduction in vivo is associated with lower amyloid plaque load in the 5XFAD mouse model of Alzheimer's disease

21 January 2018

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Etiology and pathogenesis of Parkinson's disease

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Molecular pathogenesis of Parkinson disease

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Inflammation and the degenerative diseases of aging

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Redox cycling of the herbicide paraquat in microglial cultures

21 January 2018

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CXCR4 and CXCL12 expression is increased in the nigro-striatal system of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

Presence of reactive microglia in monkey substantia nigra years after 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

Lysosomal impairment in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

α-Synuclein and protein degradation systems: a reciprocal relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12325-016-0474-7

10.1007/S12325-016-0474-7

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

6 September 2017

0 references

1 reference