Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer. (Q38762520)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27340238%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

doctoral thesis

0 references

title

Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer (English)

2 references

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15 March 2020

18 February 2022

1 reference

7

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15 March 2020

4

Robbert J C Slebos

1 reference

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15 March 2020

author name string

Josiah E Hutton

1

1 reference

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15 March 2020

Xiaojing Wang

2

1 reference

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15 March 2020

Lisa J Zimmerman

3

1 reference

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15 March 2020

Irina A Trenary

5

1 reference

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15 March 2020

Jamey D Young

6

1 reference

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15 March 2020

Daniel C Liebler

8

1 reference

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15 March 2020

Josiah Ewing Hutton

1 reference

dissertation submitted to

18 February 2022

Vanderbilt University

1 reference

18 February 2022

language of work or name

English

1 reference

18 February 2022

publication date

23 June 2016

1 reference

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15 March 2020

2016

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full work available at URL

18 February 2022

1 reference

Molecular & Cellular Proteomics

18 February 2022

published in

1 reference

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volume

15

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15 March 2020

page(s)

2924-2938

1 reference

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issue

9

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15 March 2020

thesis committee member

Daniel C. Liebler

object named as

Daniel C Liebler

1 reference

Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities

18 February 2022

cites work

1 reference

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Using Peptide-Level Proteomics Data for Detecting Differentially Expressed Proteins

6 September 2017

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Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells

6 September 2017

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Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression

6 September 2017

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Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling

6 September 2017

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Regulation of RAF protein kinases in ERK signalling

6 September 2017

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Correlation of BRAFV600E Mutation and Glucose Metabolism in Thyroid Cancer Patients: An ¹⁸F-FDG PET Study.

6 September 2017

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Large-Scale Targeted Proteomics Using Internal Standard Triggered-Parallel Reaction Monitoring (IS-PRM).

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MS-GF+ makes progress towards a universal database search tool for proteomics

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Drugging the undruggable RAS: Mission possible?

6 September 2017

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Proteogenomic characterization of human colon and rectal cancer

6 September 2017

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Exploiting the bad eating habits of Ras-driven cancers

6 September 2017

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Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer

6 September 2017

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6 September 2017

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Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

6 September 2017

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Heterogeneity of tumor-induced gene expression changes in the human metabolic network

6 September 2017

1 reference

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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

6 September 2017

1 reference

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Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

6 September 2017

1 reference

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Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics

6 September 2017

1 reference

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Targeted proteomic quantification on quadrupole-orbitrap mass spectrometer.

6 September 2017

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Parallel reaction monitoring for high resolution and high mass accuracy quantitative, targeted proteomics

6 September 2017

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Comprehensive molecular characterization of human colon and rectal cancer

6 September 2017

1 reference

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Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

6 September 2017

1 reference

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Quantitative analysis of energy metabolic pathways in MCF-7 breast cancer cells by selected reaction monitoring assay

6 September 2017

1 reference

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Precision of multiple reaction monitoring mass spectrometry analysis of formalin-fixed, paraffin-embedded tissue

6 September 2017

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Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

6 September 2017

1 reference

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Protein expression signatures for inhibition of epidermal growth factor receptor-mediated signaling

6 September 2017

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Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

6 September 2017

1 reference

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Monitoring a nuclear factor-κB signature of drug resistance in multiple myeloma

6 September 2017

1 reference

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

6 September 2017

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Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

6 September 2017

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Reversed-phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells

6 September 2017

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BRAFV600E: implications for carcinogenesis and molecular therapy

6 September 2017

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Hallmarks of Cancer: The Next Generation

6 September 2017

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Methods for peptide and protein quantitation by liquid chromatography-multiple reaction monitoring mass spectrometry

6 September 2017

1 reference

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A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer

6 September 2017

1 reference

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Mass spectrometry mapping of epidermal growth factor receptor phosphorylation related to oncogenic mutations and tyrosine kinase inhibitor sensitivity

6 September 2017

1 reference

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Quantification of beta-catenin signaling components in colon cancer cell lines, tissue sections, and microdissected tumor cells using reaction monitoring mass spectrometry

6 September 2017

1 reference

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Determination of protein stoichiometry within protein complexes using absolute quantification and multiple reaction monitoring

6 September 2017

1 reference

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Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

6 September 2017

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THE METABOLISM OF TUMORS IN THE BODY

6 September 2017

1 reference

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Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

6 September 2017

1 reference

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Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma

6 September 2017

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IDPicker 2.0: Improved protein assembly with high discrimination peptide identification filtering

6 September 2017

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Equivalence of protein inventories obtained from formalin-fixed paraffin-embedded and frozen tissue in multidimensional liquid chromatography-tandem mass spectrometry shotgun proteomic analysis.

6 September 2017

1 reference

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

6 September 2017

1 reference

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

6 September 2017

1 reference

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Cancer cell metabolism: Warburg and beyond

6 September 2017

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ProteoWizard: open source software for rapid proteomics tools development

6 September 2017

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Brick by brick: metabolism and tumor cell growth

6 September 2017

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Proteomic parsimony through bipartite graph analysis improves accuracy and transparency

6 September 2017

1 reference

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Ras oncogenes and their downstream targets

6 September 2017

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Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

6 September 2017

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6 September 2017

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6 September 2017

1 reference

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The RAF proteins take centre stage

6 September 2017

1 reference

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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

6 September 2017

1 reference

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Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

6 September 2017

1 reference

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Lactate dehydrogenase B is required for the growth of KRAS-dependent lung adenocarcinomas.

6 September 2017

1 reference

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Oncogenic and wild-type Ras play divergent roles in the regulation of mitogen-activated protein kinase signaling

6 September 2017

1 reference

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GeLC-MRM quantitation of mutant KRAS oncoprotein in complex biological samples

6 September 2017

1 reference

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Wildtype Kras2 can inhibit lung carcinogenesis in mice

6 September 2017

1 reference

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Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

25 September 2017

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Phosphatidylinositol 3-kinase activity is critical for glucose metabolism and embryo survival in murine blastocysts

23 June 2018

1 reference

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Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA).

31 August 2018

1 reference

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A Support Vector Machine based method to distinguish proteobacterial proteins from eukaryotic plant proteins

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FMCP.M116.058925

21 January 2018

Identifiers

DOI

10.1074/MCP.M116.058925

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27340238%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

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18 February 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27340238%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

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