Selected cytokine pathways in rheumatoid arthritis (Q38755912)

6 September 2017

Selected cytokine pathways in rheumatoid arthritis (English)

1 reference

6 September 2017

0 references

Mélissa Noack

1

1 reference

PubMed ID

28213794

6 September 2017

Pierre Miossec

series ordinal

2

1 reference

6 September 2017

17 February 2017

1 reference

Seminars in Immunopathology

6 September 2017

1 reference

6 September 2017

39

1 reference

6 September 2017

365-383

1 reference

6 September 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1007/s00281-017-0619-z

6 September 2017

0 references

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Signalling pathways of the TNF superfamily: a double-edged sword

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Disease-modifying antirheumatic drug-free sustained remission in rheumatoid arthritis: an increasingly achievable outcome with subsidence of disease symptoms.

21 January 2018

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21 January 2018

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Interleukin 6 is required for the development of collagen-induced arthritis

21 January 2018

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Efficacy and safety of the human anti-IL-1β monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, Phase II, dose-finding study

21 January 2018

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Tocilizumab: is there life beyond anti-TNF blockade?

21 January 2018

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The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions

21 January 2018

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Cytokine imbalance in the pathogenesis of rheumatoid arthritis: the role of interleukin-1 receptor antagonist

21 January 2018

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Immunogenicity and autoimmunity during anti-TNF therapy.

21 January 2018

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Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

21 January 2018

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MOR103, a human monoclonal antibody to granulocyte-macrophage colony-stimulating factor, in the treatment of patients with moderate rheumatoid arthritis: results of a phase Ib/IIa randomised, double-blind, placebo-controlled, dose-escalation trial

21 January 2018

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Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis

21 January 2018

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IL-17 in Chronic Inflammation: From Discovery to Targeting

21 January 2018

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Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.

21 January 2018

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T-helper-1-cell cytokines drive cancer into senescence

21 January 2018

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Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis

21 January 2018

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Evidence that cytokines play a role in rheumatoid arthritis

21 January 2018

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Regulation of tumour necrosis factor signalling: live or let die

21 January 2018

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The role of IL-1 in the pathogenesis of heart disease.

21 January 2018

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SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor

21 January 2018

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Association of HLA-DRB1 alleles with clinical responses to the anti-interleukin-17A monoclonal antibody secukinumab in active rheumatoid arthritis

21 January 2018

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Mavrilimumab, a human monoclonal antibody targeting GM-CSF receptor-α, in subjects with rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase I, first-in-human study

21 January 2018

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Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis

21 January 2018

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TNFα in the regulation of Treg and Th17 cells in rheumatoid arthritis and other autoimmune inflammatory diseases

21 January 2018

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Impact of biologic therapy on functional status in patients with rheumatoid arthritis--a meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Granulocyte-macrophage colony stimulating factor exacerbates collagen induced arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The role of IL-1β in the early tumor cell-induced angiogenic response.

21 January 2018

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Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis

21 January 2018

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IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis

21 January 2018

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Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Stromal-derived IL-6 alters the balance of myeloerythroid progenitors during Toxoplasma gondii infection

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The problem of choice: current biologic agents and future prospects in RA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Granulocyte-macrophage colony-stimulating factor is a key mediator in inflammatory and arthritic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Granulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Granulocyte/macrophage colony-stimulating factor causes a paradoxical increase in the BH3-only pro-apoptotic protein Bim in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells

21 January 2018

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Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics.

21 January 2018

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Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

21 January 2018

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Human leukocytic pyrogen: purification and development of a radioimmunoassay

21 January 2018

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Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms

21 January 2018

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Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis

21 January 2018

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Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

21 January 2018

1 reference

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Cytokine expression in synovial membranes of patients with rheumatoid arthritis and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

TNF Receptor 2 and Disease: Autoimmunity and Regenerative Medicine

21 January 2018

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Translating molecular insights in autoimmunity into effective therapy.

21 January 2018

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Role of cytokines in rheumatoid arthritis

21 January 2018

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The disease formerly known as rheumatoid arthritis

21 January 2018

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Functions of granulocyte-macrophage colony-stimulating factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Polymorphism at position -308 of the tumour necrosis factor alpha gene and rheumatoid arthritis pharmacogenetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

IL-1 pathways in inflammation and human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Recent advances in the IL-17 cytokine family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Structure and signalling in the IL-17 receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The interleukin-1 family: back to the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

One-year efficacy and safety results of secukinumab in patients with rheumatoid arthritis: phase II, dose-finding, double-blind, randomized, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Efficacy and safety of olokizumab in patients with rheumatoid arthritis with an inadequate response to TNF inhibitor therapy: outcomes of a randomised Phase IIb study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Sarilumab Plus Methotrexate in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate: Results of a Phase III Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

A phase II randomized study of subcutaneous ixekizumab, an anti-interleukin-17 monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Direct retrovirus-mediated gene transfer to the synovium of the rabbit knee: implications for arthritis gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Colony-stimulating factors in inflammation and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The roles of interleukin-6 in the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Signalling by the βc family of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Blockade of TNF-α rapidly inhibits pain responses in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: results from eight years of surveillance of clinical practice in the nationwide D

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

IL-6 controls the innate immune response against Listeria monocytogenes via classical IL-6 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

IL-17 and tumour necrosis factor α combination induces a HIF-1α-dependent invasive phenotype in synoviocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: efficacy and safety results from the randomised SARIL-RA-MOBILITY Part A trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

IL-6 as a keystone cytokine in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The activity of JAK-STAT pathways in rheumatoid arthritis: constitutive activation of STAT3 correlates with interleukin 6 levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Functional specialization of interleukin-17 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The role of IL-1 and IL-1Ra in joint inflammation and cartilage degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Directing transition from innate to acquired immunity: defining a role for IL-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Constitutive production of interleukin-6 and immunologic features in cardiac myxomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

TNF biology, pathogenic mechanisms and emerging therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Predictors for remission in rheumatoid arthritis patients: A systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The effectiveness and medication costs of three anti-tumour necrosis factor alpha agents in the treatment of rheumatoid arthritis from prospective clinical practice data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two-year prospective study (the DAMAGE study cohort).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Secukinumab for rheumatology: development and its potential place in therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Interleukin-17 family members and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Impaired immune and acute-phase responses in interleukin-6-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Acute CD4+ T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4, joint macrophages, granulocyte-macrophage colony-stimulating factor, interleukin-6, and leukemia inhibitory factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Spotlight on sirukumab for the treatment of rheumatoid arthritis: the evidence to date

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Tumor necrosis factor α induces sustained signaling and a prolonged and unremitting inflammatory response in rheumatoid arthritis synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Infections in patients with rheumatoid arthritis treated with biologic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The TNF and TNF receptor superfamilies: integrating mammalian biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Requirement of IL-17 receptor signaling in radiation-resistant cells in the joint for full progression of destructive synovitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Intracellular Signaling Pathways in Rheumatoid Arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Rilonacept in the treatment of chronic inflammatory disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Cytokines in rheumatoid arthritis - shaping the immunological landscape

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Cytokines in the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Targeting interleukin-6 in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Anakinra for rheumatoid arthritis: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The colony-stimulating factors and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

21 January 2018

Hematopoietic cytokines

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Illuminating the black box of TNF action in tuberculous granulomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Anti-interleukin 1alpha autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Targeting IL-17 and TH17 cells in chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Interleukin-17 and type 17 helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Sustained biologic-free and drug-free remission in rheumatoid arthritis, where are we now?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

IL-1beta processing in host defense: beyond the inflammasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

IL-6 is required for airway mucus production induced by inhaled fungal allergens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-017-0619-Z

The STIR-domain superfamily in signal transduction, development and immunity

21 January 2018

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Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

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IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood

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10.1007/S00281-017-0619-Z

Identifiers

DOI

1 reference

PubMed ID

28213794

Dimensions Publication ID

6 September 2017

0 references

1 reference

PubMed ID

28213794