Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. (Q37151168)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196868%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease (English)

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20 January 2020

3

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20 January 2020

author name string

Irah L King

series ordinal

1

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20 January 2020

Travis L Dickendesher

series ordinal

2

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20 January 2020

language of work or name

English

0 references

publication date

5 February 2009

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20 January 2020

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20 January 2020

volume

113

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20 January 2020

page(s)

3190-3197

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20 January 2020

issue

14

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Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii

20 January 2020

cites work

1 reference

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Tumor escape mechanism governed by myeloid-derived suppressor cells

6 September 2017

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The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

6 September 2017

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Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis

6 September 2017

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Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

6 September 2017

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Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery

6 September 2017

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Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2

6 September 2017

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CNS chemokines, cytokines, and dendritic cells in autoimmune demyelination

6 September 2017

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Blood monocytes consist of two principal subsets with distinct migratory properties

6 September 2017

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High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis

6 September 2017

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GM-CSF in inflammation and autoimmunity.

6 September 2017

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

6 September 2017

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CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis

6 September 2017

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Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

6 September 2017

1 reference

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Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

6 September 2017

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Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665891

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665891

Origin of dendritic cells in peripheral lymphoid organs of mice.

3 September 2018

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CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ T(H)-17 cells in relapsing EAE.

3 September 2018

1 reference

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Dendritic cells in multiple sclerosis lesions: maturation stage, myelin uptake, and interaction with proliferating T cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665891

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665891

The Ly-6Chigh monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice.

3 September 2018

1 reference

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Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

3 September 2018

1 reference

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TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2665891

Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis.

3 September 2018

1 reference

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Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor.

3 September 2018

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CD62L is required on effector cells for local interactions in the CNS to cause myelin damage in experimental allergic encephalomyelitis

3 September 2018

1 reference

12 December 2020

Upregulation of monocyte chemotactic protein-1 and CC chemokine receptor 2 in the central nervous system is closely associated with relapse of autoimmune encephalomyelitis in Lewis rats

1 reference

12 December 2020

Granulocyte-macrophage colony-stimulating factor induces an expression program in neonatal microglia that primes them for antigen presentation

1 reference

12 December 2020

Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis

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12 December 2020

A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells

1 reference

12 December 2020

A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells

1 reference

12 December 2020

Cutting edge: CNS CD11c+ cells from mice with encephalomyelitis polarize Th17 cells and support CD25+CD4+ T cell-mediated immunosuppression, suggesting dual roles in the disease process

1 reference

12 December 2020

CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Production of CCL2 by central nervous system cells regulates development of murine experimental autoimmune encephalomyelitis through the recruitment of TNF- and iNOS-expressing macrophages and myeloid dendritic cells

1 reference

12 December 2020

10.1182/BLOOD-2008-07-168575

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196868%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196868%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference