SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms (Q38747012)

6 September 2017

SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms (English)

1 reference

6 September 2017

1 reference

1

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31 May 2020

Valérie Petegnief

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27614878%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Coral Sanfeliu

10

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31 May 2020

author name string

Susana Revilla

2

1 reference

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31 May 2020

Suzanna Ursulet

3

1 reference

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31 May 2020

Marco Castro-Freire

4

1 reference

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31 May 2020

Perla Kaliman

5

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31 May 2020

Lydia Giménez-Llort

7

1 reference

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31 May 2020

Chamsy Sarkis

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27614878%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Mercè Pallàs

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27614878%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

1 reference

10 September 2016

1 reference

6 September 2017

Molecular Neurobiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27614878%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27614878%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

7

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31 May 2020

page(s)

5604-5619

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https://scigraph.springernature.com/pub.10.1007/s12035-016-0087-9

31 May 2020

exact match

0 references

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Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease

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Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain.

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Upregulation of miR-181 decreases c-Fos and SIRT-1 in the hippocampus of 3xTg-AD mice

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21 January 2018

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SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

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Regulation of forkhead transcription factor FoxO3a contributes to calorie restriction-induced prevention of Alzheimer's disease-type amyloid neuropathology and spatial memory deterioration

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Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH.

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The role of protein clearance mechanisms in organismal ageing and age-related diseases.

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Sirt1-deficiency causes defective protein quality control

21 January 2018

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Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

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Apomorphine treatment in Alzheimer mice promoting amyloid-β degradation

21 January 2018

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21 January 2018

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SIRT1 regulates dendritic development in hippocampal neurons

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Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling.

21 January 2018

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Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

21 January 2018

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A novel pathway regulates memory and plasticity via SIRT1 and miR-134

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21 January 2018

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21 January 2018

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Physical exercise protects against Alzheimer's disease in 3xTg-AD mice.

21 January 2018

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Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

21 January 2018

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Localization and Trafficking of Amyloid-β Protein Precursor and Secretases: Impact on Alzheimer's Disease

21 January 2018

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Blocking ADAM10 synaptic trafficking generates a model of sporadic Alzheimer's disease

21 January 2018

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Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

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5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of Alzheimer disease

21 January 2018

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Reduced amyloid-β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models

21 January 2018

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Molecular mechanisms linking amyloid β toxicity and Tau hyperphosphorylation in Alzheimer׳s disease.

21 January 2018

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Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

21 January 2018

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Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice

21 January 2018

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Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

21 January 2018

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Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau

21 January 2018

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Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1

21 January 2018

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Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons.

21 January 2018

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CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

21 January 2018

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Abeta inhibits the proteasome and enhances amyloid and tau accumulation

21 January 2018

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Sirtuins and proteolytic systems: implications for pathogenesis of synucleinopathies

21 January 2018

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A simple role for BDNF in learning and memory?

21 January 2018

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Brain-derived neurotrophic factor is reduced in Alzheimer's disease.

21 January 2018

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21 January 2018

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21 January 2018

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Lenti-GDNF gene therapy protects against Alzheimer's disease-like neuropathology in 3xTg-AD mice and MC65 cells

21 January 2018

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VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival

21 January 2018

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PGC-1 isoforms and their target genes are expressed differently in human skeletal muscle following resistance and endurance exercise.

21 January 2018

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p53 Acetylation: Regulation and Consequences

21 January 2018

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SIRT1 and Neural Cell Fate Determination

21 January 2018

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Neurodegeneration Alters Metabolic Profile and Sirt 1 Signaling in High-Fat-Induced Obese Mice

21 January 2018

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Calorie restriction and NAD⁺/sirtuin counteract the hallmarks of aging

21 January 2018

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The potential role of sirtuins regarding the effects of exercise on aging- related diseases

21 January 2018

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Neuroprotective role of trans-resveratrol in a murine model of familial Alzheimer's disease.

21 January 2018

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Resveratrol: new avenues for a natural compound in neuroprotection.

21 January 2018

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Relationship between physical activity and cognitive function in apparently healthy young to middle-aged adults: A systematic review

21 January 2018

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Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males.

21 January 2018

1 reference

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Caloric restriction improves memory in elderly humans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-016-0087-9

Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.

21 January 2018

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Small molecule SIRT1 activators for the treatment of aging and age-related diseases

21 January 2018

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SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass

21 January 2018

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The Cholinergic Antagonist Gymnodimine Improves Aβ and Tau Neuropathology in an in Vitro Model of Alzheimer Disease

21 January 2018

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Impaired proteasome function in Alzheimer's disease

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27614878

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Alzheimer's disease: genes, proteins, and therapy

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27614878